Structure of PDB 7zeb Chain 6 Binding Site BS01

Receptor Information
>7zeb Chain 6 (length=150) Species: 9940 (Ovis aries) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRAS
PRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYS
YSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQKKIKREKRLRIWYRR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7zeb Chain 6 Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zeb A universal coupling mechanism of respiratory complex I.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		C54 C55 G117 S118 C119 C149 P150
Binding residue
(residue number reindexed from 1)		C25 C26 G88 S89 C90 C120 P121
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0048038 quinone binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:7zeb, PDBe:7zeb, PDBj:7zeb
PDBsum7zeb
PubMed36104567
UniProtA0A6P7E5N1

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