Structure of PDB 7zdm Chain 6 Binding Site BS01

Receptor Information

>7zdm Chain 6 (length=156) Species: 9940 (Ovis aries) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SRGEYVVAKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFG
VVFRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGG
GYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQKKIKREKRL
RIWYRR

Ligand information

InChI=1S/4Fe.4S

LJBDFODJNLIPKO-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 2.0.7	[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385	S1[Fe]S[Fe]1.S2[Fe]S[Fe]2

Formula

Fe4 S4

Name

IRON/SULFUR CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

7zdm Chain 6 Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7zdm A universal coupling mechanism of respiratory complex I.
Resolution	3.44 Å
Binding residue (original residue number in PDB)	C54 C55 G117 S118 C119 C149 P150
Binding residue (residue number reindexed from 1)	C31 C32 G94 S95 C96 C126 P127
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0008137	NADH dehydrogenase (ubiquinone) activity
GO:0046872	metal ion binding
GO:0048038	quinone binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

	Biological Process
GO:0009060	aerobic respiration
GO:0015990	electron transport coupled proton transport
GO:0032981	mitochondrial respiratory chain complex I assembly

	Cellular Component
GO:0005739	mitochondrion

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7zdm, PDBe:7zdm, PDBj:7zdm
PDBsum	7zdm
PubMed	36104567
UniProt	A0A6P7E5N1

[Back to BioLiP]