Structure of PDB 7zai Chain 6 Binding Site BS01

Receptor Information
>7zai Chain 6 (length=92) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPLPEGNQLFGVVEQALGAGWMDVRCEDGKIRRCRIPGKLRRRVWIRVGD
LVIVQPWPVQSDKRGDIVYRYTQTQVDWLLRKGKITQEFLTG
Ligand information
>7zai Chain 2 (length=1497) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucaagggggcgucccuucugggacgccaccggcggacggcuca
guaacacgucgguaaccuacccucgggagggggauaaccccgggaaacug
gggcuaaucccccauaggccugggguacuggaagguccccaggccgaaag
ggagccguaaggcuccgcccgaggaugggccggcggccgauuagguaguu
ggugggguaacggcccaccaagccgaagaucgguacgggccgugagagcg
ggagcccggagauggacacugagacacggguccaggcccuacggggcgca
gcaggcgcgaaaccuccgcaaugcgggaaaccgcgacggggggaccccca
gugccgugccucuggcacggcuuuuccggaguguaaaaagcuccgggaau
aagggcugggcaaggccgguggcagccgccgcgguaauaccggcggcccg
agugguggccacuauuauugggccuaaagcggccguagccgggcccguaa
gucccuggcgaaaucccacggcucaaccguggggcucgcuggggauacug
cgggccuugggaccgggagaggccggggguacccccgggguaggggugaa
auccuauaaucccggggggaccgccaguggcgaaggcgcccggcuggaac
ggguccgacggugagggccgaaggccaggggagcgaaccggauuagauac
ccggguaguccuggcuguaaaggaugcgggcuaggugucgggcgagcuuc
gagcucgcccggugccguagggaagccguuaagcccgccgccuggggagu
acggccgcaaggcugaaacuuaaaggaauuggcgggggagcacuacaagg
gguggagcgugcgguuuaauuggauucaacgccgggaaccucaccggggg
cgacggcaggaugaaggccaggcugaaggucuugccggacgcgccgagag
gaggugcauggccgccgucagcucguaccgugaggcguccacuuaagugu
gguaacgagcgagacccgcgcccccaguugccagucccucccgcucggga
gggaggcacucuggggggacugccggcgauaagccggaggaaggggcggg
cgacgguaggucaguaugccccgaaacccccgggcuacacgcgcgcuaca
augggcgggacaaugggugccgaccccgaaagggggagguaauccccuaa
acccgcccucaguucggaucgcgggcugcaacucgcccgcgugaagcugg
aaucccuaguacccgcgcgucaucaucgcgcggcgaauacgucccugcuc
cuugcacacaccgcccgucacuccacccgagcggggccuaggugaggccc
gaucuccuucgggaggucgggucgagccuaggcuccgugaggggggagaa
gucguaacaagguagccguaggggaaccuacggcucgaucaccuccu
...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<<<<....>>>>>>>>.>>>>>......<<..
......<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<<....>>>
>>>.....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....
<<<<<<....>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<<..<<
<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>
>...>>>>.>>.<<<<<............>>>>>.<<<<....>>>>...
>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>
..<<<<<<<<...>>>>>>>>...<<<<<<<<.......>>>>>>>>...
..<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>.
.>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<
<<<<<<<<<....<<<<<<<<.....>>>>>>>>...>>>>>>>>..>>>
>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<<<..<<<.....
.>>>.....>>>>>>>>>..>>.......<<....>>.>>>>>>>....>
>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<.....>.
>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<...
..>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<....
..<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.<<<
<<<..<<<<<<<<<<......<<........>>..........<<<<<<<
...<<<<........<<<.<<<.......>>>.>>>......>>>>...<
<.<<<..<<<<<<<<<....<<<<<<.<<....>>...<<<<......>>
>>..>>>>>>....<<<<<.<<<<<<<..<<<..<<<<<<<<....>>>>
>>>>>>>...>>>>>>>.....<<<<<.....>>>>>........>>>>>
....>>>.>>>...>>>>>>>>....>>>>>>>...>>.>>>>>>>>...
..<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>....
.>>>>>>>......<....<<<<<<<........>>>>>>>....>....
.>>>>>>.....<<<<<<<.......>>>>>>>.......>>...>>>>>
>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<..<<<<<
<<<<<<<....>>>>>>>>>>>>..>>>>>>>>>>>>>..>>>.>>>>..
>.>>...>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7zai Role of aIF5B in archaeal translation initiation.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		A31 L32 G33 A34 R48 K54 R56
Binding residue
(residue number reindexed from 1)		A16 L17 G18 A19 R33 K39 R41
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zai, PDBe:7zai, PDBj:7zai
PDBsum7zai
PubMed35694843
UniProtQ9V138|IF1A_PYRAB Translation initiation factor 1A (Gene Name=eIF1A)

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