Structure of PDB 7of0 Chain 6 Binding Site BS01

Receptor Information
>7of0 Chain 6 (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYRE
YFGRTQQLLERKQAIQELRANVEEERAARLRTASVPLDAVRAEWERTCGP
YHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTP
TEAAQAPEVTYEAELWTLLLTSLDGHLLEPDAEYLHWLLTNIPGNRVAEG
QVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSYQLAQRTFRTFDFYKK
HQETMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKR
FPHRQPLRYLDRYRDSHEPTYGIY
Ligand information
>7of0 Chain A (length=1376) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccagacaaccuuagccaaa
ccauuuacccaaauaaaguauaggcgauagaaauugaaauggcgcaauag
auauaguaccgcaagggaaagacaagcauaauauagcaaggacuaacccc
uauaccuucugcaaugaauuaacuagaaauaacuuugcaaggagagccaa
agcuaagacccccgaaaccagacgagcuaccuaagaacagcuaaaagagc
acacccgucuauguagcaaaauagugggaagauuuauagguagaggcgac
aaaccuaccgagccuggugauagcugguuguccaagauagaaucuuaguu
caacuuuaaauuugcccacagaacccaaauccccuuguaaauuuaacugu
uaguccaaagaggaacagcucuuuggacacuaggaaaaaaccuuguagag
agaguaaaaaauuuaacacccauaguaggccuaaaagcagccaccaauua
agaaagcguucaagcucaacacaaaaaucccaaacauauaacugaacucc
ucacacccaauuggaccaaucuaucacccuauagaagaacuaauguuagu
auaaguaacaugaaaacauucuccuccgcauaagccugcgucagauacug
acaauuaacagcccaauaucuacaaucaaccaacaagucauuauuacccu
cacugucaacccaacacaggcaugcucauaaggaaagguuaaaaaaagua
aaaggaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccuc
uagcaucaccaguauuagaggcaccgccuuccuuaaauagggauggcucc
acgaggguucagcugucucuuacuuuuaaccagugaaauugaccugcccg
ugagaggcgggcauaacacagcaagacgagagacccuauggagcuuuaau
uuauuaaugcaaacaaccugcauuaaaaauuucgguuggggcgaccucgg
agcagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaag
cgaaccuuugauccaauaacuugaccaacggaacaaguuacccuagggaa
auccuauucuagaguccauaucaacaauaggguuuacgaccucguuggau
caggacaucccgauggugcagccgcuauuaaagguucguuuguucaacga
uuaaaguccuacgugaucugaguucagaccggaguaauccaggucgguuu
cuaucuacuuuaauuccucccuguacgaaaggacaagagaaauaaggccu
acuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauu
auacccacacacccaagaacaggguu
<<<.......<<<<.................................<..
....>...............<<.....>>...........>>.>>.....
........<<....>>........>>>...........<<<.......>>
>...<.<<....>>.>.<<<<<<.........<<<.<<..<<....>>..
.>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<.....>>>
...<<<..<<<<........>>>>.>>>....>>>.>>>>>...<<....
...>>......>.>>>>......>.>>..<<<<<<....<<<<....>>>
><<<.<<<<<<<<<<.....<<.......>>.....>>>>>>>>>>..>>
>.<<<<<<<<<<......>>>>>>>>>>...<<<......>>>....<<<
.<<<...<..............<....<<<.........>>>....>...
....<<<......>>>..........................>...>>>>
>>........>>>>>>...<<<<<......>>>>>.........>>>>>>
.......<<..<<<....>>><<<<..<<<<........<<<<<...>>>
>>......<<<...<<<<.......................>>>>.....
..>>>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<
<.<<.........<......<<<<<<..<<<.........>>>...<<<<
<<.............>>>>>>....<<<.<<<<.....>>>>..>>>...
.>>.>>>>.....>..>>.>>>>>>>>>>>>.>>...........<<<<<
.......>>>>>.......<<..<<<.<<<...<<<<<.<<<<<<..<<<
<<.<<<<<<<<.......>>>>>>>>>>>>>..<<<<((((.>>>><<<<
<<...........>>>>>>...<.....<<<..<<<<.....>>>>..>>
>....>.......<<<....>>>............>>>>..>>>>>>>.<
<<<<<<<<...<<.......>>...>>>>>>>>>.....)))).<<<<<.
.<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>
.....>>>>>......>>>>>.....<<<<<<<....>>>.>>>>...>>
>..>>>.>>...<<<.<<<.................>>>.>>><<<<<..
.<<<....>>>.>>>>>......<<<.<............>.>>>.....
..........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of0 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		R27 R28 R72 Y350 H351 P352 R356 H359 R360 R364 R368 T376 G378 I379 Y380
Binding residue
(residue number reindexed from 1)		R1 R2 R46 Y294 H295 P296 R300 H303 R304 R308 R312 T320 G322 I323 Y324
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of0, PDBe:7of0, PDBj:7of0
PDBsum7of0
PubMed34135319
UniProtQ96DV4|RM38_HUMAN Large ribosomal subunit protein mL38 (Gene Name=MRPL38)

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