Structure of PDB 6spf Chain 6 Binding Site BS01

Receptor Information
>6spf Chain 6 (length=38) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVRASVKKLCRNCKIIRRDGIVRVICSAEPRHKQRQG
Ligand information
>6spf Chain A (length=2885) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaagugaagaagcgcauacgguggaugccuuggcagucagaggcgaug
aaagacgugguagccugcgaaaagcuucggggagucggcaaacagacuuu
gauccggagaucucugaaugggggaacccaccuaggauaaccuagguauc
uuguacugaauccauaggugcaagaggcgaaccaggggaacugaaacauc
uaaguacccugaggaaaagaaaucaaccgagauucccuuaguaguggcga
gcgaacggggauuagcccuuaagcuucauugauuuuagcggaacgcucug
gaaagugcggccauagugggugauagccccguacgcgaaaggaucuuuga
agugaaaucaaguaggacggagcacgagaaacuuugucugaacauggggg
gaccauccuccaaggcuaaauacuacugacugaccgauagugaaccagua
ccgugagggaaaggcgaaaagaaccccggagaggggagugaaauagaacc
ugaaaccguaugcguacaagcagugggagccuacuuguuaggugacugcg
uaccuuuuguauaaugggucagcgacuuauauucaguggcaagcuuaacc
guauaggguaggcguagcgaaagcgagucuuaauagggcguuuagucgcu
ggguauagacccgaaaccgggcgaucuauccaugagcagguugaagguua
gguaacacugacuggaggaccgaacccacucccguugaaaagguagggga
ugacuuguggaucggagugaaaggcuaaucaagcucggagauagcugguu
cuccucgaaagcuauuuagguagcgccucauguaucacucugggggguag
agcacuguuucggcuagggggucaucccgacuuaccaaaccgaugcaaac
uccgaauacccagaagugccgagcaugggagacacacggcgggugcuaac
guccgucgugaaaagggaaacaacccagaccgccagcuaaggucccaaag
uugugguuaagugguaaacgaugugggaaggcuuagacagcuaggagguu
ggcuuagaagcagccacccuuuaaagaaagcguaauagcucacuagucga
gucggccugcgcggaagauguaacggggcucaaaccacacaccgaagcug
cgggugucacguaagugacgcgguagaggagcguucuguaagccugugaa
ggugaguugagaagcuugcuggagguaucagaagugcgaaugcugacaug
aguaacgacaaugggugugaaaaacacccacgccgaaagaccaaggguuc
cugcgcaacguuaaucgacgcaggguuagucgguuccuaaggcgaggcug
aaaagcguagucgaugggaaacagguuaauauuccuguacuucugguuac
ugcgauggagggacggagaaggcuaggccagcuuggcguugguuguccaa
guuuaaggugguaggcugaaaucuuagguaaauccgggguuucaaggccg
agagcugaugacgagucgucuagaugacgaagugguugaugccaugcuuc
caagaaaagcuucuaagcuucagguaaccaggaaccguaccccaaaccga
cacagguggucggguagagaauaccaaggcgcuugagagaacucggguga
aggaacuaggcaaaauggcaccguaacuucgggagaaggugcgccggcua
gggugaaggauuuacuccguaagcucuggcuggucgaagauaccaggccg
cugcgacuguuuauuaaaaacacagcacucugcaaacacgaaaguggacg
uauagggugugacgccugcccggugccggaagguuaauugaugggguuag
cgcaagcgaagcucuugaucgaagccccgguaaacggcggccguaacuau
aacgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcac
gaauggcguaacgauggcggcgcugucuccacccgagacucagugaaauu
gaaaucgcugugaagaugcaguguauccgcggcuagacggaaagaccccg
ugaaccuuuacuguagcuuugcacuggacuuugagccugcuuguguagga
uaggugggaggcuuugaagcguggacgccaguucgcguggagccauccuu
gaaauaccacccuggcaugcuugagguucuaacucugguccguaauccgg
aucgaggacaguguauggugggcaguuugacuggggcggucuccuccuaa
agaguaacggaggaguacgaaggugcgcucagaccggucggaaaucgguc
gcagaguauaaaggcaaaagcgcgcuugacugcgagacagacacgucgag
cagguacgaaaguaggucuuagugauccggugguucuguauggaagggcc
aucgcucaacggauaaaagguacuccggggauaacaggcugauaccgccc
aagaguucauaucgacggcgguguuuggcaccucgaugucggcucaucac
auccuggggcugaagccggucccaaggguauggcuguucgccauuuaaag
ugguacgcgagcuggguuuagaacgucgugagacaguucggucccuaucu
gccguggacguuugagauuugagaggggcugcuccuaguacgagaggacc
ggaguggacgaaccucugguguuccgguugucacgccaguggcauugccg
gguagcuauguucggaaaagauaaccgcugaaagcaucuaagcgggaaac
uugccucaagaugagaucucacugggaacuugauuccccugaagggccgu
cgaagacuacgacguugauaggcuggguguguaagcguugugaggcguug
agcuaaccaguacuaauggcccgugaggcuugacc
<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<....
..<<<<<<.[..(((.>>>.....<<<<<<<..<<<)))...].>>>...
..>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...(((.....<<<<<<..<<<<<..<<<...<<<....
......>>>((......<<<.....))>>>...>>>....>>>>>..>>>
>>>...........<<<<<<<<.........>>>>>>>>......<<<<<
..<<<<>>>>>..)))......]].>>>>>>>.]]...............
<<....>>....]].........<<<<.....>>>>..............
....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>.
..<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<
.....>>...>>>...<<....>>..<<.<.....>.>>.....>>>>>>
>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<
<......>>>>>>.....>>>...<<<.<<.<<........>>.>>>>>.
...>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>..
<<<<<<....<<<<<....>>>>>.<<<<<<<<..<<<<<<<<<.....<
<<...<<<.<<<<...<<................>>...>>>>.>>>..>
>.>.....>>>>>>.>>>....>>>>>>>.>...<<<<<<<<<<......
>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((....
.<<<<<<...........<<..<<<<<..<<...................
..................................................
.>>..>>>>>.>>...........)))......>>>>>>.>>>...>>>>
>>><<<<<<......>>>>>>....>>>>>>..<<<<<...<<<......
<<<<<<<<....>>>>>>>>...>>>..>>>>>........>>>>>><..
....<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<
<<<<<...<<.....>>.>>>>>>....((<<<<<<<...<<<...<<<.
...>>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<<
.<<...<<<<....<<<<..<<<..<<<<<..<<<<...((((...>>>>
..<<...<<....<<<<<<<<<<<..<<.....>>.>>>>>>>..>>>>.
...>>....>><..<<<.<<..>>.>>>...>>>>>>...>>>...>>>>
.........>>>>...>>.....>>>>>>>>>>>>>>..>>.....<<..
....>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.
<<...............<<<<<....<<..>>.....>>>>><<<<<<<<
<<<<...<<<.....>>>....>>>>>>>>>>>>............<<<<
<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>....
...>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<.......<<<<<<.<
<....>>..>>>>>>.......>>>>>>>>>..>>>>><<..........
.....>>........<...........<<<<<<.....>>>>>>.....>
....>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>
.....<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<
.[[<<<<..<<<<<.<<<.<<<<<.<<.<<<<<<<<.<.<..........
..<<<<................<<<<....>>>>................
.......>>>>...>.>.>>>>>>>>.>>...<<<.<<<<<<.....>>>
>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...
........>>>>>>..<<.....<<<<<...<<<<<.........>>>>>
.....<<.[.(((>>....>>>>>.....<<<<..<<<......>>>..>
>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>
>>>>.............>>>>..]]>>>>.......<<<<.<.<<<<<<.
..<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<
..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))
>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............
>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>
>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>
>>.>>>>.......>>>>>>>..<<<<<.....>>>>>.....<<..<<<
<<.......>>>>>....<<<.<<<<.<<<.....<<<......>>>...
.>>.>.>>>>..>>>.....>>.....>>>>>>>.
Receptor-Ligand Complex Structure
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PDB6spf Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution2.89 Å
Binding residue
(original residue number in PDB)
M1 K2 R4 A5 S6 V7 L10 R12 I16 R18 R19 D20 V23 R24 P31 R32 K34 R36 Q37 G38
Binding residue
(residue number reindexed from 1)
M1 K2 R4 A5 S6 V7 L10 R12 I16 R18 R19 D20 V23 R24 P31 R32 K34 R36 Q37 G38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6spf, PDBe:6spf, PDBj:6spf
PDBsum6spf
PubMed31611393
UniProtE2RXU2

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