Structure of PDB 7oh3 Chain 5 Binding Site BS01

Receptor Information
>7oh3 Chain 5 (length=73) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSWELKKQKRLEDKQFKERLKALKDEKEEARQAKITMLKERREKKEENER
YERLAAKMHAKKVERMRRREKRN
Ligand information
>7oh3 Chain 1 (length=3013) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaaua
agcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaag
cggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaa
uuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaaca
ggacgucauagagggugagaaucccguguggcgaggagugcgguucuuug
aaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcauuugaucagacaggccagcaucag
uuuugguggcaggauaaauccauaggaauguagcuugccugguaaguauu
auagccugugggaauacugccagcugggacugaggacugcgacguaaguc
aaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggacca
aggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaa
ugaaagugaacguagguuggggccucgcaagaggugcacaaucgaccgau
ccugaugucuucggauggauuugaguaagagcauagcuguugggacccga
aagauggugaacuaugccugaauagggugaagccagaggaaacucuggug
gaggcucguagcgguucugacgugcaaaucgaucgucgaauuuggguaua
ggggcgaaagacuaaucgaaccaucuaguagcugguuccugccgaaguuu
cccucaggauagcagaagcucguaucaguuuuaugagguaaagcgaaaac
uuuaaauauguaagaaguccuuguuugaacguggacaugaaugaagagcu
uuuagugggccauuuuugguaagcagaacuggcgaugcgggaugaaccga
acguagaguuaaggugccggaauacacgcucaucagacacacaaaaggug
uuaguucaucuagacagccggacgguggccauggaagucggaauccgcua
aggaguguguaacaacucaccggccgaaugaacuagcccugaaaauggau
ggcgcucaagcguguuaccuauacucuaccgucaggguugugaugcccug
acgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucg
ggucgaacggccucuagugcagaucuuggugguaguagcaaauauucaaa
ugagaacuuugaagacugaaguggggaaagguuccacgucaacagcaguu
ggacguggguuagucgauccuaagagauggggaagcuccguuucaaaggc
cuaggccaccaucgaaagggaauccgguuaagauuccggaaccuggauau
ggauucuucacgguaacguaacugaauguggagacgucggcgcgagcccu
gggaggaguuaucuuuucuucuuaacagcuuaucaccccggaauugguuu
auccggagauggggucuuauggcuggaagaggccagcacugcuggcuccg
gugcgcuugugacggcccgugaaaauccacaggaaggaauaguuuucaug
ccaggucguacugauaaccgcagcaggucuccaaggugaacagccucuag
uugauagaauaauguagauaagggaagucggcaaaauagauccguaacuu
cgggauaaggauuggcucuaagggucggacgaucaacuuagaacugguac
ggacaaggggaaucugacugucuaauuaaaacauagcauugcgaugguca
gaaagugauguugacgcaaugugauuucgcccagugcucugaaugucaaa
gugaagaaauucaaccaagcgcggguaaacggcgggaguaugacucucuu
aagguagccaaauggauuaacgagauucccacugucccuaucuacuaucu
agcgaaaccacagccaagggggcuuggcagaaucagcggggaagaagacc
cugugagcuugacucuaguuugacauugugaagagacauaguuucuuuac
uuauucaaugaagcggagcuggaauuauuuuccacguucuagcauucaag
gucccucggggcugauccgguugaagacauugucagguggggaguuuggg
ggcggcacaucuguuaaacgauaagcagauguccuaaggggggcucaugg
agaacagaaaucuccaguagaacaaaaggguaaaagcccccuugauuuug
auuuucagugugaauacaaaccaugaaaguguggccuaucgaucuuuagu
cccucggaauuugaggcuagaggugccagaaaguuaccacagggauaacu
ggcuuguggcagucaagcguucagcgacauugcuuuugauucuucgaugu
cggcucuuccuaucauaccgaagcagaauucgguaagcguuggauuguuc
acccacuaauagggaguagcuggguuuagaccgucgugagacagguuagu
uuacccuacugaugaauguuaccgcaauaguaauugaacuuaguacgaga
ggaacaguucauucggauaauugguuuuugcggcugucugaucaggcauu
gccgcgaagcuaccauccgcuggauuauggcugaacgccucuaagucaga
auccaugcuagaacgcggugauuucugcuccacacaauauagauggauac
gaauaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggu
gcacuuggcggaaaggccuugggugcuugcuggcgaauugcaaugucauu
uugcguggggauaaaucauuuguauacgacuuagauguacaacgggguau
uguaagcaguagaguagccuugguuacgaucugcugagauuaagccuuug
uugucugauuugu
.........................<<<<<<.....<<....>>......
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.>>>>>..<<<..<<.......<<.<<<<<<...>>>>>>.>>.......
>>....<<<<<<.<<<<<<<<<<<<<<<<<<<<<<....<<<<......>
>>>.((......<<<.....))>>>..>.>>>>>>>>..>>>>>>>>...
>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<
<..((((((>>>>>..>>>...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<.<<<<<......<<<<<<<.<<<
<<<<<<<<<<<<.....<<<<<<<<<......<<<<<<...>>>>>>...
....>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>>>
.....>>>>>>>.....>>>>>.>>>>>..<<<<........>>>><<<<
<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>...<
<....>>.......<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<
<<...<......>...>>>.>>>.>>....>>>>>>.>>>>>>..<<.<.
..<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>.
....>>>...<<<<.<<.<<........>>>>>>>>....>>>>>>>>>.
..<<.......>>......>>>>>>......>.>>..<<<<<<....<.<
<<....>>>.><<.<<<<......<<<.<<<<<<....<..<........
.>..>....>>>>...<<<<.<<<....>>>.>>>>...>>>>>....>>
>>..>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>.
..<<<<<<<..<<<<(((.....<<<<<<.....<<.........<<<.<
<<<<<<<<<.......<<<<<.<<....<<.........>>....>>...
......<<......>>...>>>>>...>>>>>>>>>>>>>..........
))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......>>>>>>
>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<
.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.....>
>.>>>>>>....((<<<<<<...<<....<<<....>>>........<<<
<..>>>>....>>....>>...<<<<<........>>>>>))<<<<.<<<
<<<<.....<<<....>>>...<.{{<<<<<<...<<<<.<<<<<<<.<<
<<<<<<<<..[[[..>>>>>><...<<<<<....<<<<<<....<<<...
..>>>....>>>>>>.....>>>>>....><<<<<<<...>>>>>>>>>>
>...>>>>>>>.>>>>.........>>>>>>...>......>>>..>>>>
>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>
>>..<<<<.....<<<<<<<.<<.........<.....<<<<<.......
........>>>>><<.<<<<<<<<<<<..>>>>>..>>>>>>.>>.....
.......<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<
.....>>>>......>>>>>>>.............<<<.<<..<<<....
.<<<<....>>>>.....>>>>>>>>........<<.<......>.>>..
........<<..>>......>>.>>>>>>>..>..>>.>>>>>>>..>>>
>>>....>>....<<<<<....>>>>>....<<<<<..<<<<......<<
<<<<<<<<<..<<<<<.<<<<<<<<..<<<<<<<<<<...>>>>>>>>>>
...<<<<<.....<<<<...<<<<.....>>>>...........}}...<
<<<<<..>>>>>>..>>>>.>>>>>.....>>>>>>>>..>>>>>.....
.<..<...<<<<<<..........>>>>>>.......<<<<<<<...<<<
<<<.......>>>>>>.....<<......>>....>>>>>>>...<<<..
<<<<.......>>>>..>>>.<<<....>>>...>.>......<<<<<..
.<<<<.))))))>>>>.>>>>>.........>>>>..>>>>>>>......
.......<<<<<<...<<.....>>...>>>>>>................
<<<<...<<<<..<.<<<<<<<......>>>>>>>...>.<<<.......
..>>>.....>>>>....>>>>......<<<<<<<....>>>.>>>>...
.>..>>>.>>>>>....<<<<<<<<..<<<<.<.<<<<<<..........
.....>>>>>>.><<<<<...<<<<...<<<<<<<<<<<]]].>>>>>..
>>>>>>..>>>>..>>>>>.<<<<...<<<<<...........>>>>>..
.>>>>.>>>>....>>>>>>>>.....<<<<<<.<<<.<<....<<....
......<<<<<<.....>>>>>>......>>.......<<<<<<...<<<
<<.<..<<<......>>>..>.>>>>>.>>>>>>.............>>.
>>>.>>>>>>..<<<<<.<..<.......>..>.....<<<<<<<<<.<<
<....<<<<....<<<<<....>>>>>...>>>>...>>>....>>>>.>
>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oh3 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		W44 K47 R51 L79 R82 R83
Binding residue
(residue number reindexed from 1)		W3 K6 R10 L38 R41 R42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oh3, PDBe:7oh3, PDBj:7oh3
PDBsum7oh3
PubMed34813592
UniProtP53188|CGR1_YEAST rRNA-processing protein CGR1 (Gene Name=CGR1)

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