Structure of PDB 6w6p Chain 5 Binding Site BS01

Receptor Information
>6w6p Chain 5 (length=64) Species: 474186 (Enterococcus faecalis OG1RF) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKQKTHRGLAKRVKRTGGGGLKRGRAFTSHRFHGKTKKQRRQLRKASMVA
KGDYKRIRQQLARM
Ligand information
>6w6p Chain A (length=2739) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaagugaauaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacuaacaccgauaugcuuuggggagcuguaaguaagcuauga
uccagagauuuccgaaugggggaacccaauaucuuuuauaggauauuacu
uuucagugaauacauagcugauuagagguagacgcagagaacugaaacau
cuuaguaccugcaggaagagaaagaaaauucgauucccugaguagcggcg
agcgaaacgggaagagcccaaaccaacaagcuugcuuguugggguuguag
gacuccgauaugguagucuguuaguauaguugaaggauuuggaaaauucc
gcuaaagagggugaaagccccguagacgaaaugcugacaacaccuaggag
gauccugaguacggcggaacacgagaaauuccgucggaauccgcggggac
caucccgcaaggcuaaauacucccuagugaccgauagugaaccaguaccg
ugagggaaaggugaaaagcaccccggaaggggagugaaauagauccugaa
accgugugccuacaacaagucaaagcucguuaaugagugauggcgugccu
uuuguagaaugaaccggcgaguuacgauugcaugcgagguuaagucgaag
agacggagccgcagcgaaagcgagucugaauagggcgaaugaguauguag
ucguagacccgaaaccaugugaucuacccauguccagguugaaggugcgg
uaaaacgcacuggaggaccgaacccacguacguugaaaagugcggggaug
agguguggguagcggagaaauuccaaacgaacuuggagauagcugguucu
cuccgaaauagcuuuagggcuagccucggaauugagaaugauggagguag
agcacuguuuggacuaguucagauaaacuccgaaugccauucauuuauau
ccgggagucagacugcgagugauaagauccguagucgaaagggaaacagc
ccagaccaccagcuaaggucccaaaauauauguuaaguggaaaaggaugu
gggguugcacagacaacuaucgagugacccugcgccgaaaauguaccggg
gcuaaacauauuaccgaagcuguggacuacaccauuagguguagugguag
gagagcguucuaagggcguugaaggucgaucgugaggacggcuggagcgc
uuagaagugagaaugccgguaugaguagcgaaagacaggugagaauccug
uccaccguaugacuaagguuuccuggggaaggcucguccgcccaggguua
gucgggaccuaagccgaggccgauaggcguaggcgauggacaacagguug
auauuccuguaccaguuguuuguuugagcaauggagggacgcaguaggcu
aaggaaugcaugcgauuggaagugcauguccaagcaaugagucuugagua
gaguuaaaugcuuuacucuuuaaggacaaguugugacggggagcgaaaua
guagcgaaguuccugacgucacacugccaagaaaagcuucuagugagaaa
acaacugcccguaccguaaaccgacacagguagucgaggagaguauccua
aggugagcgagcgaacucucguuaaggaacucggcaaaaugaccccguaa
cuucgggagaaggggugcugacuucggucagccgcagugaauaggcccaa
gcgacuguuuaucaaaaacacaggucucugcaaaaucguaagaugaagua
uaggggcugacgccugcccggugcuggaagguuaagaggauggguuagcu
ucggcgaagcucagaauugaagccccaguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgacccgcacga
aaggcguaacgauuugggcacugucucaacgagagacucggugaaauuuu
aguaccugugaagaugcagguuacccgcgacaggacggaaagaccccaug
gagcuuuacuguaguuugauauugaguguuuaacccucuaacccgcacca
cuaaucguggugggagacagugucagaugggcaguuugacuggggcgguc
gccuccuaaaagguaacggaggcgcccaaagguucccucagaaugguugg
aaaucauucgaagaguguaaaggcagaagggagcuugacugcgagaccua
caagucgagcagggacgaaagucgggcuuagugauccggugguuccgcau
ggaagggccaucgcucaacggauaaaagcuacccuggggauaacaggcuu
aucucccccaagaguccacaucgacggggagguuuggcaccucgaugucg
gcucgucgcauccuggggcuguagucggucccaaggguugggcuguucgc
ccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucgg
ucccuauccgucgcgggcguuggaaauuugagaggagcuguccuuaguac
gagaggaccgggauggacuuaccgcugguguaccaguuguucugccaagg
gcauugcuggguagcuauguagggaagggauaaacgcugaaagcaucuaa
gugugaagcccaccucaagaugagauuucccauuucuuuaagaaaguaag
accccugagagaugaucagguagauagguuggaaguggaaggcuagugau
aguuggagcggaccaauacuaaucggucgaggacuuaac
<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
..<<<<<.........>>>>>..>>.>>....<<<<<......<<....>
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<...<.<<<.<<.<<<<<<<<<.<<<...<<<.<......>.>>>
((......<<<.....))>>>...>>>...>>>>>>>>>>>>>>>.>>>>
..>>>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<
<<<>>>>>..)))......]].>>>>>>>.]]...............<<.
...>>....]].........<<<<....>>>>..................
>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<
........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<<....
.>>>...>>>...<<....>>..<<<<.....>>>>......>>>>>>>>
>>>>>..<<.<..<<<<.<<.....<<<<<<<<<..<<<....<<<<<<.
.....>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>...
.>>>>>>>>>...<<<.....>>>......>>.>>>...>..>.>>..<<
<<<<....<<<<<....>>>>><<<<<<<<..<..<<<<<<<<<.....<
<<...<<<<<<<<....>>>>>>>>..>>.>.....>>>>.>>>>>..>>
>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>
>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<
<<<<<<<........<...>....>>>>>>>>>.>>...........)))
.....>>>>>>.>>>...>>>>>>><<<<<<<......>>>>>>>....>
>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>
>>>>>>..>.....>>>>>><......<<....<<<<<<.......>>>>
>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....
((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<...
.....>>>>>))<<<<<<<.........<...<<<<....<<<<..<<<.
.<<<<<...........{...........<<..<<<<<..<<<<.<<<<<
<<<<.....>>>>>>>>>.....>>>>..>>>>>...>>...<<......
...>>....>>>>>...>>>...>>>>.........>>>>..>.......
>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>.
.>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<....
<<..>>.....>>>>><<<<<<....>>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<<....>>>......
.>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<<<<..<<.
...>>...>>>>>...>>..>>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<<.....>>>>>>.....>..
..>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<<<<<<<.<<<.<<<.>>>.>>>....<<.<<<<<
<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>>>
<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<....
...>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<...
...>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>
>>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.
<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<
<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>
>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>..
..]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<......
.........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.}..>>>
>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<...........>
>>>>...>>>>.>>>>.......>>>>>>>..<<<......>>>.....<
<<<<<<<<.......>>>>>....<<<<<<<<..<<.....<<<<....>
>>>....>>...>>>>>.>>>...>>>>....>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6w6p Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
P2 K3 Q4 K5 T6 R8 K12 R13 K15 T17 G18 G19 K23 R24 R26 A27 F28 S30 H31 R32 F33 H34 K38 K39 Q40 R42 R45 K46 D54 K56 R57 Q60 R64
Binding residue
(residue number reindexed from 1)
P1 K2 Q3 K4 T5 R7 K11 R12 K14 T16 G17 G18 K22 R23 R25 A26 F27 S29 H30 R31 F32 H33 K37 K38 Q39 R41 R44 K45 D53 K55 R56 Q59 R63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6w6p, PDBe:6w6p, PDBj:6w6p
PDBsum6w6p
PubMed33004869
UniProtA0A1B4XM73

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