Structure of PDB 6u0m Chain 5 Binding Site BS01

Receptor Information
>6u0m Chain 5 (length=597) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNE
DIYKKLSDEPSDIIPLFETAITQVAKRISINSLPTFQLILNSNANQIPLR
DLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNT
GNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNL
TMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNSGVAIRTPYIKILGIQSDV
ETVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLM
GGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKG
SSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAI
HEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQ
TTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSE
ISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTER
PITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS
Ligand information
Receptor-Ligand Complex Structure
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PDB6u0m DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S452 V453 R455 K506 A507
Binding residue
(residue number reindexed from 1)		S359 V360 R362 K413 A414
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0042555 MCM complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6u0m, PDBe:6u0m, PDBj:6u0m
PDBsum6u0m
PubMed
UniProtP29496|MCM5_YEAST Minichromosome maintenance protein 5 (Gene Name=MCM5)

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