Structure of PDB 3j46 Chain 5 Binding Site BS01

Receptor Information
>3j46 Chain 5 (length=234) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGI
DARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDL
ADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVA
EAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAK
PTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN
Ligand information
>3j46 Chain 4 (length=109) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cugaacauugagccuugauguguaggauaggugggaggcuuugaagugug
gacgccagucugcauggagccgaccuugaaauaccacccuuuaauguuug
auguucuaa
..<<<<<<<<<<..<<<<............<<<<..<........<<<<<
<........>>>>>>.....>............>>>>...>>>>..>>>>
>>>>>>...
Receptor-Ligand Complex Structure
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PDB3j46 Structure of the SecY channel during initiation of protein translocation.
Resolution10.1 Å
Binding residue
(original residue number in PDB)		M1 A2 K3 L4 T5 K6 R7 M8 R12 V15 D16 F38 D43 D51 R53 R71 K105 K106 G107 E108 N110 F111 D112 V130 L131 G132 P133 R134 R164 N165 D166 K167 N168 H172 T174 S215 M218 G219 A220
Binding residue
(residue number reindexed from 1)		M1 A2 K3 L4 T5 K6 R7 M8 R12 V15 D16 F38 D43 D51 R53 R71 K105 K106 G107 E108 N110 F111 D112 V130 L131 G132 P133 R134 R164 N165 D166 K167 N168 H172 T174 S215 M218 G219 A220
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
GO:0045947 negative regulation of translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3j46, PDBe:3j46, PDBj:3j46
PDBsum3j46
PubMed24153188
UniProtP0A7L0|RL1_ECOLI Large ribosomal subunit protein uL1 (Gene Name=rplA)

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