Structure of PDB 6yw5 Chain 44 Binding Site BS01

Receptor Information

>6yw5 Chain 44 (length=260) Species: 367110 (Neurospora crassa OR74A)

QHYLMPLRDNFEQEGIRNFLSPGSVNMAYTEYQTFILEKLNALVVGTDFE
QKDTKSIVLATARDPELAHVFNHASMAHNNHFFFDHLSPVPVKMGDKLFY
HINENFGSVDTLRDEMIGTAVSMFGPGFVWLVRTQLPGQPVALRVMATYL
AGSPYPGAHWRRQEMDAQTSIGSSPQGLSNGQRFFERSAAGFKGNKLEPT
APGGTDLIPILCLNTWEYAWLREYGTGVGGMGGKLAYAQSWWNMIDWAKV
EEEARLETRI

Ligand information

>6yw5 Chain aa (length=1435)

auagaugaguuuggugauggcucugauugaacacuguccaaauacuugac
acaugcuaaucgaacguuuaauuuuggcucuuaauuaaaagugguguaca
ggugaguauaauauuuuuucgcuuaacuuaaagugaaggcaaauccuuca
uauugcaaaaggauaucuauauccgcuuuaagaggaugagaaaaguuuca
gagauagguaguuguuaaggucauggcuuaacaagccaauaauucucuua
gucgaagcugaaaaggcugaucgaccacauugggaaugaaaaaaucccaa
ggcaaauagguacagcagugaggaaucuuggucaaugggcccacgccuga
acugguaacuuggaggaaugagacgucgauuuaucgaguaaaauucugua
uacauauugauaaugacaauauguacauuugucuugacuaauuacgugcc
agcagucgcggcaauacguaagagacuaguguuaaucaucauaaauaggu
uuaaaggguacucagacggaaaaauucgcccaaauauaggggacaauuuu
ucuagaguuuuauguaagaaggucguacucuagaguggagagauaaaauu
cugugauaccuaggggacggguaaaggcgaaggcaaucuuuuauguaaaa
acugacgucgaaggacgaaggcaaagggaacaaaaaggauuagauacccc
aguagucuuugcagacaauuaugaaugccauagguuagauuuuuaauuua
gucuauaaaugaaaguguaagcauuucaccucaagaguaaggcggcaacg
caggaacugaaaucacuagaccguuucugacaccagcaaugaaguauguu
auuuaauucggugacccacgaaaaaccuuaccacaauuugaauauuaauu
auuaauacaaguguugcacggcugucuucaguugauguugcgaaacugug
guucguuccauggaauuaacguaaacccuugcuuuauuuguaaauauuau
aaagcaguucaccuuuauauaggaaaugauaaaagggaucaagacaaguc
aucauggccuaaauauugugggcuauagacgugccacauuuuccuaaaca
aagagaugcaaaaaugugaauuuuagcuaaucucaaaaaauaggauaaaa
auauacaaggauuguagucugaaauucgacugcaugaauaagaaauugcu
aguaaucgugaaucaccaugacacggugaauauucccucggauugguacu
aaccacucgucacaugcugaaaggagugcgugcaauaaguuugcuuuucu
guuauaaguaaguagacauauagguuuagauguuauaauaggauccuucg
uaugcgcggcucugauuaguguuaagucgaaauacgguucguguagugga
aguugcacgggacuuaucaauguugaacaauacga

......((((..<<<<<<.))))<<<<<.<<<<<..<<<<<.<<.....<
<<.<<<..<<<..<<.<<<<<<<..<<.>>..>>>>>>>.>>>>>.....
.<<.........<<<<<<<.<<<...<<<<<<<<<<<<<.....>>>>>.
..........<<<<<<..>>>>>>>>>>>>>>.>>.>.(>>>>>>>...<
<<<<..<<<..<<<<<<<<....)..>>>>>>>>>>>......>>>>>..
<<<<.<<<<.....>>>>...>>>>.>>.<<<<<...........>>>>>
.<<......>>...>>>>>>.........<<<....<<<<....>>>>..
>>>..>>..>>>>>.<<<<......<<<<....>>>>.....>>>>....
<<<<<<<<<.......>>>>>>>>>.....<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>>.........<<<
((.....<<..<..<<<.<<<<<<<<.<<<<.......>>>..>>>>>>>
>>...<<<<<......<<<<<<<.<..<<<<<<.<<<..<<<......>>
>.....>>>>>>>>>..>........<<....>>.>>>>>>>......>>
>>>...>>>...>.>>....<<<<<<...<<.....<<.........>>.
....>>>>>>>>..........<<<<<<.<<<<<<<<<<<<...>>>>>>
>>>>>>..<<..))>>....>>>>>>.>>>.<<........<<<....>>
>......>>..>>>>>><<<<<...<<<<<....<<<<<<...<<<<<<<
<<......<<........>>..........<<<<<<<.....<<<<<<<.
>>>>>>>..<<.<<...<.<<<<<<<....<<<<<<<<<....>>>.<<<
<......>>>>...>>>>>>.....<<<<<<<<<<<<...........>>
>>>>>>..<<.<<<......>>>....>>....>>>>.....>>>.>>>.
..>.>.>>>>....>>>>>>>...>>.>>>>>>>.......<<<<<....
..<<<..<<..<<<<....>>>>..>>....>>>......>>>>>.....
.......<....<<<<<<<........>>>>>>>....>.....>>>>>>
....<<<<<<...........>>>>>>..........>>>>>..>>>.>>
....<.<<<.<..<<<<<<<..<<<<<.<<<<<<....<.......<<<<
<<<<<<<.....<<<<<......>>>>>....>>>>>>>>>>>.....>.
..>>>>>>>>>>>..>>>>>>>...>.>>>..>.....<<<<<<<<<...
.>>>>>>>>>.........................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6yw5 Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
• Resolution: 2.85 Å
• Binding residue (original residue number in PDB): L101 R105 P198 G199 P244 G245 G246
• Binding residue (residue number reindexed from 1): L59 R63 P156 G157 P202 G203 G204

Gene Ontology

Molecular Function

• GO:0004784 superoxide dismutase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006801 superoxide metabolic process
• GO:0019430 removal of superoxide radicals

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion

External links

• PDB: RCSB:6yw5, PDBe:6yw5, PDBj:6yw5
• PDBsum: 6yw5
• PubMed: 33056988
• UniProt: Q7S2H6|RT26_NEUCR Small ribosomal subunit protein mS42 (Gene Name=rsm26)