Structure of PDB 8iue Chain 4 Binding Site BS01

Receptor Information
>8iue Chain 4 (length=365) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YFKDKVTGVGPPANEDTREKAAQGIKAFEELLVTKWKNWEKALLRKSVVS
DRLQRLLQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQDINQL
PEEALLGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWS
REEEERLQAIAAAHGHLEWQKIAEELGTSRSAFQCLQKFQQHNKALKRKE
WTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPG
LKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLH
FSLKKGRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIM
MGKKQGLRRRRRRAR
Ligand information
>8iue Chain X (length=74) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atatgcttaccgtaacttgaaagtatttcgatttcttggctttatatatc
ttgtggaaaggacgcttcggcagc
Receptor-Ligand Complex Structure
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PDB8iue Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		K183 K345 E348 W349 K393 Q438 D441 R442 R445 K453 W456
Binding residue
(residue number reindexed from 1)		K35 K197 E200 W201 K245 Q290 D293 R294 R297 K305 W308
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000995 RNA polymerase III general transcription initiation factor activity
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0016251 RNA polymerase II general transcription initiation factor activity
Biological Process
GO:0042795 snRNA transcription by RNA polymerase II
GO:0042796 snRNA transcription by RNA polymerase III
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0019185 snRNA-activating protein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8iue, PDBe:8iue, PDBj:8iue
PDBsum8iue
PubMed37165065
UniProtQ5SXM2|SNPC4_HUMAN snRNA-activating protein complex subunit 4 (Gene Name=SNAPC4)

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