Structure of PDB 8inf Chain 4 Binding Site BS01 |
>8inf Chain 4 (length=611) Species: 9606 (Homo sapiens)
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AHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKV KFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINI AKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYL EQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFT TKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAV LYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSE DDQKIFTDLQSEGFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGN KVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKRMETEESRKKRERDL ELEMGDDYILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLE ELEKEEELRTAAGEYDSVSESEDEEMLEIRQLAKQIREKKKLKILESKEK NTQGPRMPRTAKKVQRTVLEKEMRSLGVDMDDKDDAHYAVQARRSRSSRT PRDVSGLRDVKMVKKAKTMMKNAQKKMNRLGKKGEADRHVFDMKPKHLLS GKRKAGKKDRR |
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>8inf Chain 2 (length=3654)
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cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc agcggaggagaagaaacuaaccaggauucccucaguaacggcgagugaac agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggacau guggcguacggaagacccgcuccccggcgccgcucguggggggcccaagu ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg caguccgcccggaggauucaacccggcggcggguccggccgugucggcgg cccggcggaucuuucccgcgcgggggaccgucccccgaccggcgaccggc cgccgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccggg acggcugggaaggcccggcggggaagguggcucgggggcccccgaguguu acagcccccccggcagcagcacucgccgaaucccggggccgagggagcga gacccgucgccgcgcucuccccccucccggcgcgccggggggggccgggc caccccucccacggcgcgaccgcucggggcggacuguccccagugcgccc cgggcgggucgcgccgucgggcccgggggaggccacgcgcgcgucccccg aagagggggacggcggagcgagcgcacggggucggcggcgacgucggcua cccacccgacccgucuugaaacacggaccaaggagucuaacacgugcgcg agucgggggcucgcacgaaagccgccguggcgcaaugaaggugaaggccg gcgcgcucgccggccgaggugggaucccgaggccucuccaguccgccgag ggcgcaccaccggcccgucucgcccgccgcgccggggagguggagcacga gcgcacguguuaggacccgaaagauggugaacuaugccugggcagggcga agccagaggaaacucugguggagguccguagcgguccugacgugcaaauc ggucguccgaccuggguauaggggcgaaagacuaaucgaaccaucuagua gcugguucccuccgaaguuucccucaggauagcuggcgcucucgcagacc cgacgcccgccacgcaguuuuauccgguaaagccuuuaaauggguaagaa gcccggcucgcuggcguggagccgggcguggaaugcgagugccuaguggg ccacuuuugguaagcagaacuggcgcugcgggaugaaccgaacgccgggu uaaggcgcccgaugccgacgcucaucagaccccagaaaagguguugguug auauagacagcaggacgguggccauggaagucggaauccgcuaaggagug uguaacaacucaccugccgaaucaacuagcccugaaaauggauggcgcug gagcgucgggcccauacccggccgucgccggcagucgagaguggacggga gcggcggcccggagccccgcggacgcuacgccgcgacgaguaggagggcc gcugcggugagccuugaagccuagggcgcgggcccggguggagccgccgc aggugcagaucuuggugguaguagcaaauauucaaacgagaacuuugaag gccgaaguggagaaggguuccaugugaacagcaguugaacaugggucagu cgguccugagagaugggcgagcgccguuccgaagggacgggcgauggccu gcccuccgaucgaaagggagucggguucagauccccgaauccggaguggc ggagaugggcgccgcgaggcguccagugcgguaacgcgaccgaucccgga gaagccggcgggagccccggggagaguucucuuuucuuugugaagggcag ggcgcccuggaauggguucgccccgagagaggggcccgugccuuggaaag cgucgcgguuccggcggcguccggugagcucucgcuggcccuugaaaauc cgggggagaggguguaaaucucgcgccgggccguacccauauccgcagca ggucuccaaggugaacagccucuggcauguuggaacaauguagguaaggg aagucggcaagccggauccguaacuucgggauaaggauuggcucuaaggg cugggucggucgcggccggcgccuagcagccgacuuagaacuggugcgga ccaggggaauccgacuguuuaauuaaaacaaagcaucgcgaaggcccgcg gcggguguugacgcgaugugauuucugcccagugcucugaaugucaaagu gaagaaauucaaugaagcgcggguaaacggcgggaguacucucuuaagaa cgagauucccacugucccuaccuacuauccagcgaaaccacagccaaggg aacgggcuuggcggaaucagcggggaaagaagacccuguugagcuugacu cuagucuggcacggugaagagacaugagagguguagaauaagugggaggc ccccggcgcccccccgguguccccgcgaggggcccggggcgggguccgcc ggcccugcgggccgccggugaaauaccacuacucugaucguuuuuucacu gacccggugaggcgggggggcgagccccgaggggcucucgcuucuggcgc caagcgcccggccgcgcgccggccgggcgcgacccgcuccggggacagug ccagguggggaguuugacuggggcgguacaccugucaaacgguaacgcag guguccuaaggcgagcucagggaggacagaaaccucccguggagcagaag ggcaaaagcucgcuugaucuugauuuucaguacgaauacagaccgugaaa gcggggccucacgauccuucugaccuuuuggguuuuaagcaggagguguc agaaaaguuaccacagggauauuguggcggccaagcguucauagcgacgu cgcuuuuugcuucgaugucggcucuuccuaucauugugaagcagaauuca ccaagcguuggauuguucacccacuaauagggaacgugagcuggguuuag accgucgugagacagguuaguuuuacccuacugaugauguguuguugcca ugguaauccugcucaguacgagaggaaccgcagguucagacauuuggugu augugcuuggcugaggagccaauggggcgaagcuaccaucugugggauua ugacugaacgccucuaagucagaaucccgcccaggcggaacgauacggca gcgccgcggagccucgguuggccucggauagccggucccccgccgggguc cggugcggagugcccuucguccugggaaacggggcgcggccggagaggcg gccgcccccucgcccgucacgcaccgcacguucguggggaaccuggcgcu aaaccauucguagacgaccugcuucugggucgggguuucguacguagcag agcagcucccucgcugcgaucuauugaaagucagcccucgacacaagggu uugu |
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PDB | 8inf Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. |
Resolution | 3.0 Å |
Binding residue (original residue number in PDB) | K7 V11 D20 L23 Q27 R28 K29 T32 K36 R42 M48 R49 K50 L66 D90 K93 L94 L96 Q98 N100 I101 K118 R125 K127 K130 R131 A132 G135 R136 T139 R143 R160 R190 Y198 F200 H209 R216 N234 K491 I495 S498 K499 K501 Q504 P509 R510 R575 K588 M592 K594 Q597 N601 K605 R611 D615 H620 K625 R626 K627 A628 G629 K630 K631 D632 R633 R634 |
Binding residue (residue number reindexed from 1) | K6 V10 D19 L22 Q26 R27 K28 T31 K35 R41 M47 R48 K49 L65 D89 K92 L93 L95 Q97 N99 I100 K117 R124 K126 K129 R130 A131 G134 R135 T138 R142 R159 R189 Y197 F199 H208 R215 N233 K490 I494 S497 K498 K500 Q503 P508 R509 R552 K565 M569 K571 Q574 N578 K582 R588 D592 H597 K602 R603 K604 A605 G606 K607 K608 D609 R610 R611 |
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Enzyme Commision number |
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