Structure of PDB 8ev3 Chain 4 Binding Site BS01

Receptor Information
>8ev3 Chain 4 (length=211) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFIKKLAANDRKTRDKALESLQRFLSQKKKFERLDFLKLWKGLFYCMWMA
DKPLYQQKLSDNLAALVPIVWIDNRILFQSTFWETMGREWTGIDILRTDK
FYLLMRRFCAAAFRDIQTRSKTALLDKVVAEYNQMWMDGPFNTENLAFPN
GILFHLADIWTEELRKVYPEDVPKADWYLPFDSTIKSSHNVVLRKTLPKR
LDRVSEYTKDS
Ligand information
>8ev3 Chain 1 (length=1452) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaauggguggucaucuaaagc
uaaauauuggcgagagaccgauagcgaacaaguagagugaucgaaagaug
aaaagaacuuugaaaagagaguuaaauaguacgugaaauugcugaaaggg
aagcauuggaaaucagucuuaccugggugagaucaguagucucucgagac
uaugcacucugaaccugugguaggucagcaucaguuuucgggggcggaaa
aagaauaagggaagguggcuguuuauagcccuuguuguaauacguccacu
ggggacugaggacugcggcuugccaaggaugcugacauaaugguuuucaa
uggcccgucuugaaacacggaccaaggagucuagcaucuaugcgaguguu
ugggugaugaaaacccauccgcgaagugggaacgcccuuguggcgugcac
caucagagcauagcuguugggacccgaaagauggugaaccaucuaguagc
ugguuccugccgaaguuuccggauagcagaaacucagaucaguuuuauga
guauguaaaaugagaguuucuagugggccauuuuugguaagcagaacugg
cgaugcgggaugaaccgaacgugagguuaaggugccggaauguacgcuca
ucagacgaaaagguguuaguucauaugaacuagcccugggcgcuuaagcg
uacuacccauaccucaccgucuggguuagcuuugagaagcucagacgagu
aggcaggcguggagguuugugacgaagccuugggcgugagccugggucga
acagccucuagugcagaucuugguggaaguagcuagaucuagcgaaacca
cagccuggggaacgggccaggcucauaccgaagcagaauucgguaagcuc
gucgcaaugguaauucaacuuaguacgagaggaaccguugauucagauca
uugguauuugcggccgcggagcuaucaucugccggauaacggcugaacgc
cucuaagccagaauccgugccagaaagcgacgauuauguauaaaaauaga
gguaggcuacucuccuguaucguagaagaugggcgaugguugaugaaacg
gaaguguuuuauugacuuguccaugaaauuccaugaauccauugcauacg
acuuuaauguggaacgggguauuguagauuaagccuuuguucccaagauu
ug
........................<<<<<<........>>>>>.>.....
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<..<<.
......<<.<<<<<<<.......>>>>>>>.>>.......>>....<<<<
<.<<<<<..<<<<<..<<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>>..>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<..>>>>>..>>>
..................................<<....>>........
.......<<<<....>>>>...............................
...<<<<<<<<<<<<.....<<<.<<<<.<<<.<<.<<<<<<<..>>>>>
>>>>...>>>..>>>>..>>>..<<<<<<<.<<<<<<<<<<<<<<<....
.....<<<<<<.................>>>>>>........>>>>>.>>
>>>>>>>>........<<<..>>>.....>>>>>>>....>>>>>>>>>>
>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<..
.<<<<.......>>>>...>>>...<<<<..<<<<<.....>>>>>...>
>>>....>>>>>>.>>>>>>..<<.<..<<<<<<<..>>>>>>>.....>
.>>..<<<<<<....<.<<..>>.><<<<<<<<<....<<<.<<<<<<<.
...>>>>>>>>>>.>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>
>....<<<......>>>...<<<<<<<...<<<(((.....<<<<<<...
..<<......<<<.<<<<<<<<<..>>>>>>>>>>>>.))).>>...>>>
>>>.>>>...>>>>>>><<<<<<<<<............>>>>>>>>>...
.>>>>>>..<<<<<<<..<<......<<<<.<<<<....>>>>>>>>...
>>.>>>>>>>........>>>>>><<.....<<<<<..>>>>>....>>.
...<<<<<........>>>>>....<<<<<<<......>>>>>>>...<<
<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<..
..<<<....<<<..>>>...>>>...>>>>>.<<<<....<<<<......
.....>>>>....>>>>.>>>>....>>>>>>>......<<.......<<
<<..<..>..>>>>....>>........<<<<<....<<<<<<<<<<<<.
.....>>>>>>>>>>>>..>>>>>..........<<<<<.<.........
....>.....<<<<<<<<<.<<<...>>>....>>>>.>>>>>...>>>>
>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ev3 Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K17 K200
Binding residue
(residue number reindexed from 1)		K12 K195
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0006364 rRNA processing
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030688 preribosome, small subunit precursor

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ev3, PDBe:8ev3, PDBj:8ev3
PDBsum8ev3
PubMed36423630
UniProtQ9Y7M6|RRP1_SCHPO Ribosomal RNA-processing protein 1 homolog (Gene Name=SPBC9B6.07)

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