Structure of PDB 8buu Chain 4 Binding Site BS01

Receptor Information
>8buu Chain 4 (length=37) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVRPSVKPICEKCKVIRRKGKVMVICENPKHKQKQG
Ligand information
>8buu Chain A (length=2852) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacgaacaccgauaugcuucggggagcuguaagcaagcuuuga
uccggagauuuccgaauggggaaacccaccacucguaauggagugguauc
cauaucugaauucauaggauaugagaaggcagacccggggaacugaaaca
ucuaaguacccggaggaagagaaagcaaaugcgauucccugaguagcggc
gagcgaaacgggauuagcccaaaccaagaggcuugccucuugggguugua
ggacacucuguacggaguuacaaaggaacgagguagaugaagaggucugg
aaaggcccgccauaggagguaacagcccuguagucaaaacuucguucucu
ccugaguggauccugaguacggcggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaagag
auccugaaaccgugugccuacaaguagucagagcccguuaacgggugaug
gcgugccuuuuguagaaugaaccggcgaguuacgaucccgugcaagguua
agcagaagaugcggagccgcagcgaaagcgagucugaauagggcgcauga
guacguggucguagacccgaaaccaggugaucuacccauguccaggguga
aguucagguaacacugaauggaggcccgaacccacgcacguugaaaagug
cggggaugagguguggguaggggugaaaugccaaucgaaccuggagauag
cugguucucuccgaaauagcuuuagggcuagccucaagguaagagucuug
gagguagagcacugauuggacuaggggccgguuaccgaauucagucaaac
uccgaaugccaaugacuuauccuugggagucagacugcgagugauaagau
ccguagucgaaagggaaacagcccagaccgccagcuaaggucccaaagua
uacguuaaguggaaaaggauguggaguugcuuagacaacuggucgaguga
cucugcgccgaaaauguaccggggcuaaacguaucaccgaagcugcggac
uguucgaacagugguaggagagcguucuaagggcugugaagccagaccgg
aaggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaa
gaggggugagaauccccuccaccgaaugccuaagguuuccugaggaaggc
ucguccgcucaggguuagucgggaccuaagccgaggccgaaaggcguagg
cgauggacaacagguugauauuccuguaccaccuccucaccauuugagca
auggggggacgcaggaggauaggguaagcgcgguauuggauauccgcguc
caagcaguuaggcugggaaauaggcaaauccguuucccauaaggcugagc
ugugauggcgagcgagcgaaguuccugauuccacacugccaagaaaagcc
ucuagcgaggugagaggugcccguaccgcaaaccgacacagguaggcgag
gagagaauccuaaggugaucgagagaacucucguuaaggaacucggcaaa
augaccccguaacuucgggagaaggggugcucuguuagggugcaagcccg
agagagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggu
cucugcgaagccguaaggcgaaguauaggggcugacgccugcccggugcu
ggaagguuaagaggagcgcuuagcguaagcgaaggugcgaauugaagccc
caguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuu
gucggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacuguc
ucaacgagagacucggugaaauuauaguaccugugaagaugcagguuacc
cgcgacaggacggaaagaccccguggagcuuuacugcagccugauauuga
auguugguacagcuuguacaggauagguaggagccuuggaaaccggagcg
ccagcuucgguggaggcaucggugggauacuacccuggcuguauugaccu
ucuaacccgccgcccuuaucgggcggggagacagugucaggugggcaguu
ugacuggggcggucgccuccuaaaagguaacggaggcgcccaaagguucc
cucagaaugguuggaaaucauucgcagaguguaaaggcacaagggagcuu
gacugcgagaccuacaagucgagcagggacgaaagucgggcuuagugauc
cggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccg
gggauaacaggcuuaucucccccaagaguccacaucgacggggagguuug
gcaccucgaugucggcucaucgcauccuggggcuguagucagucccaagg
guugggcuguucgcccauuaaagcgguacgcgagcuggguucagaacguc
gugagacaguucggucccuauccgucgcgggcgcaggaaauuugagagga
gcuguccuuaguacgagaggaccgggauggacgcaccgcugguguaccag
uuguucugccaagggcaucgcuggguagcuaugugcggacgggauaagug
cugaaagcaucuaagcaugaagccccccucaagaugagauuucccauucc
gcaaggaaguaagaucccugaaagaugaucagguugauaggucugaggug
gaaguguggcgacacauggagcugacagauacuaaucgaucgaggacuua
ac
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<<<<<<<.........>>>>>>>.>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>...<<<<......<<...
..>>.....>>>>...(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<.....<<<<.......<<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>>>>
>>.>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
........>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<..
.<<<.....>>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<<
<.....<<<...<<<<<<<<...<<.<<..>>..>>...>>>>>>>>..>
>.>.....>>>>.>>>>>..>>>>>>>.>>..<<<<<<<.<<......>>
.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<
<<<<<...........<<..<<<<<<<<<........<<..>>....>>>
>>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<
<<<<..>>>>>>....>>>>>>..<<<<<<<.<<......<<<<<.<<..
..>>.>>>>>...>>.>>>>>>>........>>>>>><......<<....
<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.
....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>
>...>>...<<<<<........>>>>>))<<<<<.<<<<<<......<<.
..<<<<....<<<<..<<<..<<<.<<<<<<<<...(((....>>>>>><
<..<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>....>>>>..>>
>>>...>><..<<..>>...>>>>>>...>>>...>>>>.........>>
>>..>>..>>>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<
<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<............
...<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>.
..>>>>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<
<<..<<<...<<...<<<<<..<<....>>...>>>>>...>>...>>>>
>>>>..>>>>><<<<<<.......>>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>>...>>.>>>>>>>.....>
>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<
<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<
<.<<<<<<<<<<<<...........<<<<<..<<<......<<<<<<<<.
...>>>>>>>>...>>>............>>>>>..>>>>>>>>>>>>.>
>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>.
.<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<
<...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>.
..<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]......
<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>
>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....>
>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>
>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<
....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<.
.<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<
<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<
<<...........>>>>>....>>>.>>>>.......>>>>>>>..<<<<
....>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<.
...<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>
>.
Receptor-Ligand Complex Structure
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PDB8buu Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
M1 K2 R4 P5 S6 V7 K8 I10 K15 R18 R19 K20 P30 K31 K33 K35 Q36 G37
Binding residue
(residue number reindexed from 1)
M1 K2 R4 P5 S6 V7 K8 I10 K15 R18 R19 K20 P30 K31 K33 K35 Q36 G37
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8buu, PDBe:8buu, PDBj:8buu
PDBsum8buu
PubMed36951104
UniProtP20278|RL36_BACSU Large ribosomal subunit protein bL36 (Gene Name=rpmJ)

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