Structure of PDB 7qi5 Chain 4 Binding Site BS01

Receptor Information
>7qi5 Chain 4 (length=38) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FKNKTVLKKRCKDCYLVKRRGRWYVYCKTHPRHKQRQM
Ligand information
>7qi5 Chain A (length=1558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccca
cuaccuaaaaaaucccaaacauauaacugaacuccucacacccaauugga
ccaaucuaucacccuauagaagaacuaauguuaguauaaguaacaugaaa
acauucuccuccgcauaagccugcgucagauuaaaacgaacugacaauua
acagcccaauaucuacaaucaaccaacaagucauuauuacccucacuguc
aacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaa
cucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuagcauc
accaguauuagaggcaccgccugcccagugacacauguuuaacggccgcg
guacccuaaccgugcaaagguagcauaaucacuuguuccuuaaauaggga
ccuguaugaauggcuccacgaggguucagcugucucuuacuuuuaaccag
ugaaauugaccugcccgugaagaggcgggcauaacacagcaagacgagaa
gacccuauggagcuuuaauuuauuaaugcaaacaguaccuaacaaaccca
cagguccuaaacuaccaaaccugcauuaaaaauuucgguuggggcgaccu
cggagcagaacccaaccuccgagcaguacaugcuaagacuucaccaguca
aagcgaacuacuauacucaauugauccaauaacuugaccaacggaacaag
uuacccuagggauaacagcgcaauccuauucuagaguccauaucaacaau
aggguuuacgaccucgauguuggaucaggacaucccgauggugcagccgc
uauuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguuc
agaccggaguaauccaggucgguuucuaucuacuuucaaauuccucccug
uacgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccg
uaaaugauaucaucucaacuuaguauuauacccacacccacccaagaaca
ggguuugu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>...<<<......>>>....<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
...........................>...>>>>>>........>>>>>
>...<<<<<......>>>>>.........>>>>>><......<<..<<<.
...>>><<<<..<<<<........<<<<<..<.....>..>>>>>.....
.<<<...<<<<.......................>>>>.......>>>..
...<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<...
......<......<<<<<<..<<<.........>>>...<<<<<<.....
........>>>>>>....<<<.<<<..<<<<<....>>>..>>>>><<<<
<<......>>>>>>........<...........<<<<<<.....>>>>>
>.....>....>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>
>.....>.....<<<<<........>>>>>.......<<..<<<.<<...
...<<<<.<<<<<<..<<<<<.<<<<<<<<....<<<........<<<..
..>>>.......>>>......>>>>>>>>>>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<.....<<<..<<<<.....>>>>.
.>>>...........>>.........<<<....>>>............>>
>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>>
>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>>
>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>...
.<<<<<<<....>>>.>>>>....>>..>>>.>>...<.<<<.<<<....
.............>>>.>>><<<<<...<<<....>>>.>>>>>......
<<<................>>>......>..........<<<<.......
>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qi5 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Resolution2.63 Å
Binding residue
(original residue number in PDB)		F66 T70 L72 K73 K74 R75 K83 R84 R85 G86 W88 Y89 Y91 P96 R97 K99 R101 M103
Binding residue
(residue number reindexed from 1)		F1 T5 L7 K8 K9 R10 K18 R19 R20 G21 W23 Y24 Y26 P31 R32 K34 R36 M38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0016604 nuclear body
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qi5, PDBe:7qi5, PDBj:7qi5
PDBsum7qi5
PubMed38769321
UniProtQ9P0J6|RM36_HUMAN Large ribosomal subunit protein bL36m (Gene Name=MRPL36)

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