Structure of PDB 7ohw Chain 4 Binding Site BS01

Receptor Information
>7ohw Chain 4 (length=217) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFVKQLSSNNRKTRVNALEALKKYLTAKQFKENKQIEFNKLWKGLYYAMW
FSDRPRPQQRLANELGELHGLYFDPKDNSTADELTTNDKAFIKFSRGFWK
VMCFEWFNIDRYRLDKYLLLIRRVLFSQLKYLQSRNWDKKLVDEYIKKVL
RWLPLSGSPKVYTGIPIHIVDILLDEWERLLKKTPLDVIIFQDIVADYNN
SKVLREKIKEDLFSDTR
Ligand information
>7ohw Chain 1 (length=1639) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuauaucaauaagc
ggaggaaaagaaaccaaccgggauugccuuaguaacgcgagugaagcggc
aaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauuug
gagagggcaacuuuggggccguuccuugucuauguuccuuggaacaggac
gucauagagggugagaaucccguguggcgaggagugcgguucuuuguaaa
gugccuucgaagagucgaguuguuugggaaugcagcucuaaguggguggu
uccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacagu
gauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaaa
uuguugaaagggaagggcauuugaucagacaugguguuuugugcccucug
cuccuuguggguaggggaaucucgcauuucacugggccagcaucaguuuu
gguggcaggauaaauccauaggaauguagcuugccucgguaaguauuaua
gccugugggaauacugccagcugggacugaggacugcgacguaagucaag
gaugcuggcauaaugguuauaugccgcccgucuugaaacacggaccaagg
agucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaauga
acgagguuggggccucgcaagaggugcacaaucgaccgauccugaggaug
gauuugguaagagcauagcuguugggacccgaaagauggugaaaaccauc
uaguagcugguuccugccgaaguuucccucaggauagcagaagcucguau
caguuuuaugaaaaugaagagcuuuuagugggccauuuuugguaagcaga
acuggcgaugcgggaugaaccgaacguagaguuaaggugccggaauacac
gcucaucagacacaaaagguguuaguucaucuagacagccggacgguggc
cauggaagucggaauccgcuaaggaguguguaacaacucaccggccgaau
gaacuagcccugaggauggcgcucaagcguguuaccuauacucuaccguc
aggguugauaugaugcccugacgaguaggcaggcguggaggucagugacg
aagccuagaccguaaggucgggucgaacggccucuagugcagaucuuggu
gguaguagcagcgaaaccacagccaaggaacgguugggcuugggcaguca
agcgcgacauugcuauaccgaagcagaauucgguaauguuaccgcaauag
uaauugaacuuaguacgagaggaacaguucauucggauaauugguuuuug
cggcugucuaucaggcauugccgcgaagcuacauccgcuggauuauggcu
gaacgccucuaagucagaauccaugcuagaacgcggugaugcuccacaca
gauggauacgaauaaggcguccuuguggcgucgcugaaccauagcaggcu
agcaacggugcacuuggcggaaaggccuugggugcuugcuggcgaauugc
aaugcguggggauaaaucauuuguauacgacuuagauguacaacggggua
uuguaagcagcugcugagauuccuuuguugucugauuug
..........................<<<<<<.....<..>......>>>
>>.>.........<<....>>..<<<<<......<<....>>.....>>>
>>..<<<..<........<<.<<<<<<...>>>>>>.>>........>..
..<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......>>>>.
((......<<<.....))>>>....>>>>>>>>>..>>>>>>>....>>>
>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<.
.>>>>>>..>>>..................................<<..
..>>...............<<<......>>>...................
...............<<<<<.<<<<<<.....<<<<...<<<..<<<<<<
<<<.....>>>>>>>>>......>>>...>>>>..<<<<<<<.<<<<<<<
<<<<<<<<.....<<<<<<<<<......<<<<<......>>>>>......
.>>>>>>>>..>.>>>>>.>>>>>>>>>>........<<<....>>>...
..>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<<<<<.
...<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>.......
....<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<.......>
>>>.>>>>....>>>>>>.>>>>>>..<<.<..<<<<<<<....>>>>>>
>.....>.>>..<<<<<<....<.<........>.><<<<<<<<<....<
<<.<<<<...>>>>>>>..>>>>>>>.>>..<<<<.<<<.<.....>.>>
>.>>>>....<<<......>>>...<<<<<<<..<<<<(((.....<<<<
<<.....<<.......<<<.<<<<<<<<<<.......<<<<<.<<....<
<.........>>....>>.........<<......>>...>>>>>...>>
>>>>>>>>>>>......))).>>...>>>>>>.>>>>..>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>><.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.>>....>>....<<<<.......>>>>.....<<<<<...
.<..>....>>>>>.<<<<<<<......>>>>>>>..<<<<<<<<..<<<
<.<.<<<<<<...............>>>>>>.><<<<<...<<<<....<
<<<<<<<.<...>.>>>..>>>>>...>>>>.>>>>>.<<<<...<<<<<
...........>>>>>...>>>>.>>>>....>>>>>>>>.<<<<<<...
...<<..........<<<<<<.....>>>>>>......>>.......<<<
<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>>>.......
.....>>>>>>.<<<<<<.<..<.......>..>.....<<<<<<<<<.<
<<....<<<..>>>...>>>.>>>.>>>>>>..>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ohw Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R15 R58 R60 P61 R115
Binding residue
(residue number reindexed from 1)		R11 R54 R56 P57 R111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0030688 preribosome, small subunit precursor

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ohw, PDBe:7ohw, PDBj:7ohw
PDBsum7ohw
PubMed34813592
UniProtP35178|RRP1_YEAST Ribosomal RNA-processing protein 1 (Gene Name=RRP1)

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