Structure of PDB 1po2 Chain 4 Binding Site BS01

Receptor Information
>1po2 Chain 4 (length=62) Species: 12081 (Human poliovirus 1 Mahoney) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPI
KDVLIKTAPMLN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1po2 Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		G2 A3 Q4 V5
Binding residue
(residue number reindexed from 1)		G1 A2 Q3 V4
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1po2, PDBe:1po2, PDBj:1po2
PDBsum1po2
PubMed15299887
UniProtP03300|POLG_POL1M Genome polyprotein

[Back to BioLiP]