Structure of PDB 1piv Chain 4 Binding Site BS01

Receptor Information
>1piv Chain 4 (length=62) Species: 12088 (Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAQVSSQKVGAHENSSTINYTTINYYKDSASNAASKQDYSQDPSKFTEPL
KDVLIKTAPALN
Ligand information
>1piv Chain 0 (length=4) Species: 12088 (Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ISEV
Receptor-Ligand Complex Structure
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PDB1piv Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		A3 Q4 V5
Binding residue
(residue number reindexed from 1)		A2 Q3 V4
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

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Molecular Function
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Cellular Component
External links
PDB RCSB:1piv, PDBe:1piv, PDBj:1piv
PDBsum1piv
PubMed15299834
UniProtP03302|POLG_POL3L Genome polyprotein

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