Structure of PDB 1ar8 Chain 4 Binding Site BS01

Receptor Information
>1ar8 Chain 4 (length=60) Species: 12081 (Human poliovirus 1 Mahoney) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAQVSSQKVGAHESTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKD
VLIKTAPMLN
Ligand information
>1ar8 Chain 0 (length=8) Species: 12081 (Human poliovirus 1 Mahoney) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAASSST
Receptor-Ligand Complex Structure
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PDB1ar8 Structural studies of poliovirus mutants that overcome receptor defects.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		A3 Q4 V5 S6
Binding residue
(residue number reindexed from 1)		A2 Q3 V4 S5
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ar8, PDBe:1ar8, PDBj:1ar8
PDBsum1ar8
PubMed9253417
UniProtP03300|POLG_POL1M Genome polyprotein

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