Structure of PDB 8uge Chain 3R Binding Site BS01

Receptor Information
>8uge Chain 3R (length=196) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHTDIRVPDFSDYRRAEVLDSTKSSKESSDARKGFSYLITATTTVGVAYA
AKNAVSQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRH
RTKKEIDQEAAVEVSQLRDPQHDLERVKKPEWVILIGVCTHLGCVPIANA
GDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPTYEFTSDDLVIVG
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8uge Chain 3R Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8uge High-resolution in situ structures of mammalian respiratory supercomplexes.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		C217 H219 C222 C236 C238 H239 S241
Binding residue
(residue number reindexed from 1)		C139 H141 C144 C158 C160 H161 S163
Annotation score1
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uge, PDBe:8uge, PDBj:8uge
PDBsum8uge
PubMed38811722
UniProtA0A480EHC1

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