Structure of PDB 6gsl Chain 3I Binding Site BS01

Receptor Information
>6gsl Chain 3I (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRK
VAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGV
YDAAGVKDRKKSRSKYGTKKPK
Ligand information
>6gsl Chain 13 (length=1512) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuguuggagaguuugauccuggcucagggugaacgcuggcggcgugccua
agacaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcg
gacgggugaguaacgcgugggugaccuacccggaagagggggacaacccg
gggaaacucgggcuaaucccccauguggacccgccccuuggggugugucc
aaagggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugg
ugggguaauggcccaccaaggcgacgacggguagccggucugagaggaug
gccggccacaggggcacugagacacgggccccacuccuacgggaggcagc
aguuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuu
ggaggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccc
ccgacgaggggacugacgguaccgggguaauagcgccggccaacuccgug
ccagcagccgcgguaauacggagggcgcgagcguuacccggauucacugg
gcguaaagggcguguaggcggccuggggcgucccaugugaaagaccacgg
cucaaccgugggggagcgugggauacgcucaggcuagacggugggagagg
gugguggaauucccggaguagcggugaaaugcgcagauaccgggaggaac
gccgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaa
agcguggggagcaaaccggauuagauacccggguaguccacgcccuaaac
gaugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaa
gcgcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauuga
cgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcg
aagaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugg
ggugccccgcgaggggagcccuagcacaggugcugcauggccgucgucag
cucgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgc
cguuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaa
agcgggaggaaggaggggacgacgucuggucagcauggcccuuacggccu
gggcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaa
cggggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaa
cccgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccg
cggugaauacguucccgggccuuguacacaccgcccgucacgccauggga
gcgggcucuacccgaagucgccgggagccuacgggcaggcgccgagggua
gggcccgugacuggggcgaagucguaacaagguagcuguaccggaaggug
cggcuggacacc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<.
.<<<.<<<..<<<..<<.<<<<<<<<<<<...>>>>>>>>>>>.>>>>>.
.....<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<
<......>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>
>..<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<
<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>.
..>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>
>>>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..
<<<<......<<<<....>>>>.....>>>>....<<<<<.........<
<<.....>>>...........>>>>>......<<<<<(((...<<<<<..
...<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<
<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<
.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<
<<<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>....
.......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>...
.<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>.......
...<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....
>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>
..........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>
>....<<......>>...>>>>>>>>.<<<.<<<..<<<<<<.......<
<<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<
<<<<<<...<...<<<.....>>>>.....>>>>>>>.....<<<<<...
.>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>
>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....
>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<.....
...>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>
>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..
<<<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>
>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gsl Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution3.16 Å
Binding residue
(original residue number in PDB)		P5 T6 N8 Q9 R12 R15 E16 K20 V24 G29 P31 F32 R33 K46 K47 N49 S50 A51 R53 K54 K57 E73 R86 G87 R89 K91 D92 P94 R97 R113 K114 K115 S116 R117 S118 K119 T122 K123 K124
Binding residue
(residue number reindexed from 1)		P1 T2 N4 Q5 R8 R11 E12 K16 V20 G25 P27 F28 R29 K42 K43 N45 S46 A47 R49 K50 K53 E69 R82 G83 R85 K87 D88 P90 R93 R109 K110 K111 S112 R113 S114 K115 T118 K119 K120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gsl, PDBe:6gsl, PDBj:6gsl
PDBsum6gsl
PubMed29931292
UniProtQ5SHN3|RS12_THET8 Small ribosomal subunit protein uS12 (Gene Name=rpsL)

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