Structure of PDB 6lqs Chain 3F Binding Site BS01

Receptor Information
>6lqs Chain 3F (length=437) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKDIIASRLKEDVAEQQGRVFRYFGDKLLISEAKQSFTRVGENNLTCISC
FQPVLNKYTFEESSNNKGRLFAYTVSKDLQLTKYDITDFSKRPKKLKYAK
GGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWST
ESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQL
EILYGHHDIVEDISALAMERCVTVGARDRTAMLWKIPDETRLTFRGGDEP
QKLLRRWMKEPLFFCEGSIDVVSMVDDFHFITGSDNGNICLWSLAKKKPI
FTERIAHGILPEPSFNDISGETDEELRKRQLQGKKLLQPFWITSLYAIPY
SNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGKHG
KEKFRILASIAKEHRLGRWIANVSGARNGIYSAVIDQ
Ligand information
>6lqs Chain 3A (length=234) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guaccccagagugagaaauagcuuggccgaaucgguucggccacuauauu
gccguugcauuuuauggcgcgaugaucuugacccauccuaucuucgaaga
uagggggguggguacaaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<..<<....<............<<<<<<<<<..>>>>>>>>>.......
<<<............>>>........>...<<<..<<<<<<<<<..>>>>
>>>>>.>>>.>>.>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6lqs Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R151 G153 K182 R207 K209 L211 A218 S264 E266 S267 K545 R551 R560 N561
Binding residue
(residue number reindexed from 1)		R39 G41 K67 R92 K94 L96 A103 S149 E151 S152 K412 R418 R427 N428
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqs, PDBe:6lqs, PDBj:6lqs
PDBsum6lqs
PubMed32943522
UniProtQ06506|RRP9_YEAST Ribosomal RNA-processing protein 9 (Gene Name=RRP9)

[Back to BioLiP]