Structure of PDB 6gsl Chain 3E Binding Site BS01

Receptor Information
>6gsl Chain 3E (length=207) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPS
DYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLD
NVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKS
RNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQL
VIEFYSR
Ligand information
>6gsl Chain 13 (length=1512) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuguuggagaguuugauccuggcucagggugaacgcuggcggcgugccua
agacaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcg
gacgggugaguaacgcgugggugaccuacccggaagagggggacaacccg
gggaaacucgggcuaaucccccauguggacccgccccuuggggugugucc
aaagggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugg
ugggguaauggcccaccaaggcgacgacggguagccggucugagaggaug
gccggccacaggggcacugagacacgggccccacuccuacgggaggcagc
aguuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuu
ggaggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccc
ccgacgaggggacugacgguaccgggguaauagcgccggccaacuccgug
ccagcagccgcgguaauacggagggcgcgagcguuacccggauucacugg
gcguaaagggcguguaggcggccuggggcgucccaugugaaagaccacgg
cucaaccgugggggagcgugggauacgcucaggcuagacggugggagagg
gugguggaauucccggaguagcggugaaaugcgcagauaccgggaggaac
gccgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaa
agcguggggagcaaaccggauuagauacccggguaguccacgcccuaaac
gaugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaa
gcgcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauuga
cgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcg
aagaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugg
ggugccccgcgaggggagcccuagcacaggugcugcauggccgucgucag
cucgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgc
cguuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaa
agcgggaggaaggaggggacgacgucuggucagcauggcccuuacggccu
gggcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaa
cggggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaa
cccgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccg
cggugaauacguucccgggccuuguacacaccgcccgucacgccauggga
gcgggcucuacccgaagucgccgggagccuacgggcaggcgccgagggua
gggcccgugacuggggcgaagucguaacaagguagcuguaccggaaggug
cggcuggacacc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<.
.<<<.<<<..<<<..<<.<<<<<<<<<<<...>>>>>>>>>>>.>>>>>.
.....<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<
<......>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>
>..<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<
<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>.
..>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>
>>>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..
<<<<......<<<<....>>>>.....>>>>....<<<<<.........<
<<.....>>>...........>>>>>......<<<<<(((...<<<<<..
...<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<
<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<
.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<
<<<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>....
.......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>...
.<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>.......
...<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....
>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>
..........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>
>....<<......>>...>>>>>>>>.<<<.<<<..<<<<<<.......<
<<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<
<<<<<<...<...<<<.....>>>>.....>>>>>>>.....<<<<<...
.>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>
>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....
>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<.....
...>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>
>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..
<<<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>
>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>.......
Receptor-Ligand Complex Structure
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PDB6gsl Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution3.16 Å
Binding residue
(original residue number in PDB)
R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 Q62 R65 E72 R73 Q74 N77 K85 K86 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 D134 L135 P136 S137 K151 L157 E205 S208 R209
Binding residue
(residue number reindexed from 1)
R1 I3 P5 V6 C7 R8 R11 R12 K20 G21 E22 R23 K28 R33 R34 Y36 P38 G39 Q40 H41 Q43 R47 S50 Y52 A53 Q60 R63 E70 R71 Q72 N75 K83 K84 S111 R113 Q114 R116 Q117 R120 H121 H123 R130 D132 L133 P134 S135 K149 L155 E203 S206 R207
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gsl, PDBe:6gsl, PDBj:6gsl
PDBsum6gsl
PubMed29931292
UniProtP80373|RS4_THET8 Small ribosomal subunit protein uS4 (Gene Name=rpsD)

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