Structure of PDB 6gsk Chain 32 Binding Site BS01

Receptor Information
>6gsk Chain 32 (length=208) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRP
SDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRL
DNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEK
SRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQ
LVIEFYSR
Ligand information
>6gsk Chain 1G (length=1490) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuguuggagaguuugauccuggcucagggugaacgcuggcggcgugccua
agacaugcaagucgugcgggccgcgggguacuccguggucagcggcggac
gggugaguaacgcgugggugaccuacccggaagagggggacaacccgggg
aaacucgggcuaaucccccauguggacccgccccuugggguguguccaaa
gggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggugg
gguaauggcccaccaaggcgacgacggguagccggucugagaggauggcc
ggccacaggggcacugagacacgggccccacuccuacgggaggcagcagu
uaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuugga
ggaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccg
acgaggggacugacgguaccgggguaauagcgccggccaacuccgugcca
gcagccgcgguaauacggagggcgcgagcguuacccggauucacugggcg
uaaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuc
aaccgugggggagcgugggauacgcucaggcuagacggugggagagggug
guggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgcc
gauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagc
guggggagcaaaccggauuagauacccggguaguccacgcccuaaacgau
gcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcg
cgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacgg
gggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaag
aaccuuaccaggccuugacaugcuagggaacccgggugaaagccuggggu
gcccuagcacaggugcugcauggccgucgucagcucgugccgugaggugu
uggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcggu
ucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggaggg
gacgacgucuggucagcauggcccuuacggccugggcgacacacgugcua
caaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgcaa
aaaggugggcccaguucggauuggggucugcaacccgaccccaugaagcc
ggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguucccg
ggccuuguacacaccgcccgucacgccaugggagcgggcucuacccgaag
ucgccgggagccuacgggcaggcgccgaggguagggcccgugacuggggc
gaagucguaacaagguagcuguaccggaaggugcggcugg
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<.
.<<<.<<<..<<<..<<.<<<<<<<<<<..>>>>>>>>>>.>>>>>....
..<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<..
....>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..
<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<
<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>
>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>
>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<
<......<<<<....>>>>.....>>>>....<<<<<......<.<<<<.
....>>>>..>.......>>>>>......<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<...
..>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.
<<<<<<<.<<.<<<<<<..<<<<<<<<<<.......<........>....
.......<<<<<<<......<<<<<<<....<.<<<<....>>>>.>...
..>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>..
<<<<......>>>>..>>>>>>.....<<<<.<<<<<<...<<...<<<.
....>>>.>>....>>>>>>.....<<<<<....>>>>>........>>>
>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.
....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>..
...>>>>>>>...........<<<<<<<........>>>>>>>.......
...>>>>>>....<<<<<<<..........>>>>>>>......>>...>>
>>>>>>>>.>>.......<<.<.<<<<.<<<..<<<<<<<<<<<<<...<
.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>..>>>.>>>
>..>.>>.........<<<<<<<<<....>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB6gsk Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution3.36 Å
Binding residue
(original residue number in PDB)
G2 I5 V8 C9 R10 R13 R14 E24 R25 K30 R36 Y38 P40 G41 Q42 H43 Q45 Y54 L58 R59 Q62 R65 R66 S71 E72 R73 Q74 K84 K86 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 D134 L135 S137 L155 R209
Binding residue
(residue number reindexed from 1)
G1 I4 V7 C8 R9 R12 R13 E23 R24 K29 R35 Y37 P39 G40 Q41 H42 Q44 Y53 L57 R58 Q61 R64 R65 S70 E71 R72 Q73 K83 K85 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 D133 L134 S136 L154 R208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gsk, PDBe:6gsk, PDBj:6gsk
PDBsum6gsk
PubMed29931292
UniProtP80373|RS4_THET8 Small ribosomal subunit protein uS4 (Gene Name=rpsD)

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