Structure of PDB 8d8l Chain 3 Binding Site BS01

Receptor Information

>8d8l Chain 3 (length=244) Species: 4932 (Saccharomyces cerevisiae)

IHVVPKLPNSKALLQNGVPNILSSSGFKTVWFDYQRYLCDKLTLATAGQS
LESYYPFHILLKTAGNPLQSNIFNLASSIHNNHLFVENILPSAKTEPSRL
FLSKIKDSFNGSDWEVVKEEMIYRAENEVLGQGWLFLVENNEKKLFILTS
NNNGTPYYFPRNQSFDLNSAISIDEFATLKQMKELIGKSTKLNGKVQDWT
MPIICVNLWDHAYLHDYGVGNRSKYVKNVLDNLNWSVVNNRIFS

Ligand information

>8d8l Chain a (length=1506)

uaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacaca
ugcgaaucauacguuuauuauugagauaauaaauaugugguguaaacgug
aguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacuuaau
auuauauaaaaauaauuuauauaauaaaaaggauauauauauauauauuu
aucuauagucaagccaauaaugguuuagguaguagguuuauuaagaguua
aaccuagccaacgauccauaaucgauaaugaaaguuagaacgaucacguu
gacucugaaauauagucaauaucuauaagauacagcagugaggaauauug
gacaaugaucgaaagauugauccaguuacuuauuaggaugauauauauau
auauauaaauugauuaaaaauaaaauccauaaauaauuaaaauaaugaua
uuaauuaccauauauuuauauggauauauauauauuuuaauaguccugac
uaauauuugugccagcagucgcgguaacacaaagagggcgagcguuaauc
auaaugguuuaaaggauccguagaaugaauuauauauaauuuagaguuaa
uaaaauauaauuaaagaauuauaauaguaaagaugaaauaauaauaauaa
uuauaagacuaauauaugugaaaauauuaauuaaauauuaacugacauug
agggauuaaaacuagaguagcgaaacggauucgauacccguguaguucua
guaguaaacuaugaauacaauuauuuauaauauauauauaaauaauaaau
gaaaaugaaaguauuccaccugaagaguacguuagcaauaaugaaacuca
aaacaauagacgguuacagacuuaagcaguggagcauguuauuuaauucg
auaauccacgacuaaccuuaccauauuuugaauauuauaauaauuauaau
uauuauauuacaggcguuacauuguugucuuuaguucgugcugcaaaguu
uuagauuaaguucauaaacgaacaaaacuccauauauauaauuuuaauua
uauauaauuuuauauuauuuauuaauauaaagaaaggaauuaagacaaau
cauaaugauccuuauaauauggguaauagacgugcuauaauaaaaugaua
auaaaauuauauaaaauauauuuaauuauauuuaauuaauaauauaaaac
auuuuaauuuuuaauauauuuuuuuauuauaauaugaauuauaaucugaa
auucgauuauaugaaaaaagaauugcuaguaauacguaaauuaguauguu
acggugaauauucuaacuguuucgcacuaaucacucaucacgcguugaaa
cauauuauuaucuuauuauuuauauaauauuuuuuaauaaauauuauuaa
uuuauauuuauuuauaucagaaauaauaugaauuaaugcgaaguugaaau
acaguuaccguaggggaaccugcggugggcuuauaaauaucuuaaauauu
cuuaca

...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<......<<<.
<<<..<<<..<<<<<<<<<<<<..>>>>>>>>>>..>>>>>.....<<<.
.......<<<<<.<<.........<<<<<<<<.<<<<.......>>>>..
.<<<<<<<<<.....>>>>>>>>>......<<<<<<<<<..>>>>>>>>>
.>>>>>>>>....>>>>>>><<<....<<<..<<<<<<<<........>>
>>>>>>>>>......>>>..<<<<.<<<<....>>>>...>>>>.>>><<
<<<<.........>>>>>><<<<.....>>>>..>>>>>>.........<
<<...<<<<<....>>>>.>>>>...>.>>>>>>.<<<<..<<<<<<...
.>>>>>>..<<......>>.....>>>>..<<<<<<<<............
..>>>>><<<<<<<..>>>>>>>.<<<<..>>>>.>>>....<<<<<(((
.....<<<<.....<<.)))>>.......>>>>.>>>>>..>>>>>>>>>
.....<<<((.....<<<<...<.<<.<<<<<<..>>>>>>...<<<<<<
<<.....<<<<<<<<<..<<<<<<<....<...........>.......>
>>>>>>..>>.......<<....>>.>>>>>>>..>>>>>>>>...>>>.
..>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>
>>..........<<<<<<.<<<<<<<<<<<<..>>.>>>>>>>>>>..<<
..))>>....>>>>>>.>>>.<<.......<<<<....>>>>.....>>.
.)))).]<<.<<...<<<<......<<<<<..<<<<<<<<<<........
....................<<<<<<<.....<<.<<<<<<<<<<..>>>
>>>>>>>.>>.<<<.<<..<<<<<<<<<<<<..<<<<<<<<<....>>>.
...<<......>>....>>>>>>.....<<<.<<<<<<<<........>>
>>>>>>..<<<<<<<<<.....>>>>>>>>>....>>>...>>>>>>>..
..>>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<...
.....<<<..<<..<<<<<<......>>>>>>..>>....>>>......>
>>>>>......<<<<<.<....>.>>>>>.....<....<<<<<<<....
....>>>>>>>....>.....>>>>>.....<<.<<<<<.........>>
>>>>>...........>>>>..>>..>>....<.<<<.<.<<<<<<<<..
<<<<<<<<<.<<<...<<<..<<<.<<<<<...<<<<<<<...>>>>>>>
...>>>>>>>>..>>>..>>>>>>>>>>>>..>>>>>>>>..>.>>.>.>
.....<<<<<<<<<....>>>>>>>>>.......................
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8d8l Principles of mitoribosomal small subunit assembly in eukaryotes.
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): Y61 F64 H65 K69 Q76 Y175 N211 M219
• Binding residue (residue number reindexed from 1): Y54 F57 H58 K62 Q69 Y157 N193 M201

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0004784 superoxide dismutase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006801 superoxide metabolic process
• GO:0019430 removal of superoxide radicals
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8d8l, PDBe:8d8l, PDBj:8d8l
• PDBsum: 8d8l
• PubMed: 36482135
• UniProt: P47141|RT26_YEAST Small ribosomal subunit protein mS42 (Gene Name=RSM26)