Structure of PDB 8csq Chain 3 Binding Site BS01

Receptor Information
>8csq Chain 3 (length=45) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRRKVQEGRLRRKQIKFEKDLRRIWLKAGLKEAPEGWQTPKIYLR
Ligand information
>8csq Chain A (length=802) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaaaaauagacuacgaaaguggcuuuaacauau
cugaacacacaauagcuaagacccaaacugggauuagauaccccacuaug
cuuagcaacaguuaaaucaacaaaacugcucgccagaacacuacgagcca
cagcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggag
ccuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucag
ccuauauaccgccaucuuaacccugaugaaggcuacaaaguacguuaggu
caagguguagcccaugagguggcaagaaaugggcuacauuuucuacccca
gaaaauuuagcaguaaacugagaggcuuaguugaacagggcccugaagcg
cgucgucacccuccucaaguauacuucaaaggacauuuaacuaaaacccc
uacgcauuuauauagaggagacaagucguaaaguguacuggaaagugcac
uu
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<..<.<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>>........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<..............<<....>>.>>>>>>.....>
>>>...>>>>.....<<<<<...<<...<<<<.........>>>>...>>
>>>>>.<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<..
..>>>>.....>>..>>>>>>.....<<<<<<<<...<<<.<<<<<.<<<
<<<<<<<<......<<................>>.<<<<<<<.......<
<.<<<..<<<<<<<.<...<<<<<.....>>>.......>>..>.>.>>>
...>>>>>>>>....>>>>>>>..>>>.>>>>>>>.>...<<<<.....>
>>>..>>>>>.....<<<<<<<...>>>>>>>.....>>>...>>>>>>>
>..<<.....<<<<<<..<<<<<......<<<...<<<.....>>>..>>
>.......>>>>>.>>>>>>......>>..<<<<<<<<<....>>>>>>>
>>
Receptor-Ligand Complex Structure
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PDB8csq Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.54 Å
Binding residue
(original residue number in PDB)
R161 R164 K165 K171 Y195 R197
Binding residue
(residue number reindexed from 1)
R9 R12 K13 K19 Y43 R45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
GO:0045839 negative regulation of mitotic nuclear division
GO:0045862 positive regulation of proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8csq, PDBe:8csq, PDBj:8csq
PDBsum8csq
PubMed36482135
UniProtQ9NWT8|AKIP_HUMAN Small ribosomal subunit protein mS38 (Gene Name=AURKAIP1)

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