Structure of PDB 7ryh Chain 3 Binding Site BS01

Receptor Information
>7ryh Chain 3 (length=38) Species: 480119 (Acinetobacter baumannii AB0057) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVQASVKKICGSCKVIRRNGVIRVICSAEPRHKQRQG
Ligand information
>7ryh Chain A (length=2685) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaaguaauuaagugcaugugguggaugccuuggcagucagaggcgaug
aaagacgugauagccugcgaaaagcuccggggaggcggcaaauauccuuu
gauccggagaugucugaaugggggaacccaccuacuuuaagguagguauu
gcaacaugaauacauaguguugcaaggcgaacgaggggaagugaaacauc
ucaguacccuuaggaaaagaaaucaauugagauucccucaguagcggcga
gcgaacggggaucagcccauuaaguuauguguguuuuaguggaacgcucu
gggaagugcgaacguagagggugauauucccguacacgaaagggcacaca
uaaugaugacgaguagggcgaggcacgugaaaccuugucugaauaugggg
ggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccagu
accgugagggaaaggcgaaaagaaccccugugaggggagugaaauagauc
cugaaaccgcaugcauacaagcagugggagcaccuucguggugugacugc
guaccuuuuguauaaugggucagcgacuuauauucaguagcgagguuaac
cguauaggggagccguagagaaaucgagucuuaauagggcguuuaguugc
uggguauagacccgaaaccaggcgaucuauccaugagcagguugaagguu
ggguaacacuaacuggaggaccgaacccacugucguugaaaagccagggg
augacuuguggauaggggugaaaggcuaaucaagccuggugauagcuggu
ucuccccgaaagcuauuuagguagcgccucggacgaauaccauagggggu
agagcacuguuucggcaccgaugcaaacuccgaauaccuaugaguacuau
ccgggagacagacugcgggugcuaacguccguagucaagaggaaaacaau
ccagaccgccagcuaaggccccaaaaucauaguuaagugggaaacgaugu
gggaaggcauagacagcuauagucgagucggccugcgcggaagauguaac
ggggcuaaaacuaugugccgaagcugcggauguauacuuuguauacgugg
uaggggagcguucuguaagccgaugaagguguguugagaagcaugcugga
gguaucagaagugcgaaugcugacgugaguaacgacaaaacgggugaaaa
acccguucgccgaaagaccaaggguuccaguccaacguuaaucggggcug
ggugagucgaccccuaaggcgaggccgaaaggcguagucgaugggaaaau
gguuaauauuccauuacuucuguguaaugcgaugagaggacggagaaggc
uaaaucagccuggcguugguuguccaggugaaaggauguaggcaaugcug
agaucugauagcaagcuguacuugugcagcgaagugguugaugccaugcu
uccaggaaaagucucuaagcuucaguuacacaggaaucguacccgaaacc
gacacagguggucaggucgaguagaccaaggcgcuugagagaacucugcu
gaaggaacuaggcaaaaugguaccguaacuucgggagaagguacgcuguu
guuggugauggaacucgcuuccugagcugacgacagccgcagaaaccagg
ccgcugcaacuguuuauuaaaaacauagcacucugcaaacacgaaagugg
acguauagggugugaugccugcccggugcuggaagguuaauugauggggu
uagcguaagcgaagcucuugaucgaagccccaguaaacggcgccuaaggu
agcgaaauuccuugucggguaaguuccgaccugcacgaauggcauaauga
uggcggcgcugucuccagcagaggcucagugaaaucgaaaucgcugugaa
gaugcaguguacccgcggcuagacggaaagaccccgugaaccuuuacugc
agcuugacacugaacuuugauugagguucuaacucugucccgugauccgg
gacgaggaccgugucugguggguaguuugacuggggcggucuccuccuaa
agaguaacggaggaguacgaaggugcgcucagcguggucggaaaucacgc
guagaguauaaaggcaaaagcgcgcuuaacugcgagacccacaagucgag
cagguacgaaaguaggucuuagugauccggugguucuguauggaagggcc
aucgcucaacggauaaaagguacucuggggauaacaggcugauaccgccc
aagaguucauaucgacggcgguguuuggcaccucgaugucggcucaucuc
auccuggggcugaagcaggucccaaggguauggcuguucgccauuuaaag
agguacgcgagcuggguuuagaacgucgugagacaguucggucccuaucu
accgugggcgcuggaaauuugagaggaucugcuccuaguacgagaggacc
agaguggacgaaccucugguguaccgguugugacgccagucgcaucgccg
gguagcuauguucggaagggauaaccgcugaaagcaucuaagcgggaagc
cuaccucaagauaagauuucccuaggacuuuauguccucuaaagagccgu
ucgagacuaggacguugauagguuggauguggaagcauagugauauguga
agcugaccaauacuaauugcucgugaggcuugacu
<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<....
..<<<<<<....(((.>>>.....<<<<<<<..<<.)))......>>...
..>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...<<<......<<<<<<<<<<<<<..<<<...<<<.<.
.....>.>>>((......<<<.....))>>>...>>>....>>>>>>>>>
>>>>...........<<<<<<<<.........>>>>>>>>......<<<<
<..<<<<>>>>>..>>>......]].>>>>>>>.]]..............
.<<....>>....]].........<<<<.....>>>>.............
.....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>
...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<
<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>
>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<
<<......>>>>>>.....>>>...<<<.<<<.<........>.>>>>>>
....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>.
.<<<<<<....<<<<<....>>>>>.<<<<<<<....<<<<<<<<<....
.<<<...<<<.<<<<..>>>>.>>>..>>.>.....>>>>>>.>>>...>
>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<......>
>>...<<<<.<<<...<<<(((.....<<<<<<...........<<.<<<
<<<..<<.........<<..>>.....>>..>>>>>>>>...........
)))......>>>>>>.>>>...>>>>>>><<<<<<<<...>>>>>>>>..
..>>>>>><.<<<<<...<<<......<<<<<<<<....>>>>>>>>...
>>>..>>>>>..>.....>>>>>><......<<.....<<<<<<......
.>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>
>....((<<<.<<<...<<<...<<<....>>>...>>>...>>>..<<<
<<........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<..<<<
..<<<<<<<<<<<...((((...>>>>>>....<<<<...<<<<.>>>>.
..>>>>........<<<<<......>>>>>....>>>>>...>>>...>>
>>.........>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<
......>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<
<.<<...............<<<<<....<<..>>.....>>>>><<<<<<
<<<<<<...<<<<.....>>>>...>>>>>>>>>>>>............<
<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.
......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<........<<<<<
..<......>...>>>>>........>>>>>>>>..>>>>>.........
.<...........<<<<<<.....>>>>>>.....>....>>>>>..>>.
>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<....
....>>>>>..<<<<<<<.<<<<.[[......<<<<.[[<<<<..<<<<.
.<<<.<<<<<.<<<<<<<<..>>>>>>>>...<<<.<<<<<<.....>>>
>>>>>>....>>>>>.>>>...>>>>..<<<<.....>>>><<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>
.....<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>
>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>
>>>>.............>>>>..]]>>>>.......<<<<...<<<<<<.
..<<.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<
..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..>>>
>>>>>>>>....<<<<<<<...<<<<..<<<<<<................
.>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>
>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>
>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<<<<<<
<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>..
.>>...>>>>>.>>>...>>>>..>..>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ryh An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii.
Resolution2.43 Å
Binding residue
(original residue number in PDB)
M1 K2 A5 S6 K15 R19 N20 R24 R32 K34 R36 Q37
Binding residue
(residue number reindexed from 1)
M1 K2 A5 S6 K15 R19 N20 R24 R32 K34 R36 Q37
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ryh, PDBe:7ryh, PDBj:7ryh
PDBsum7ryh
PubMed35100868
UniProtB7IA18|RL36_ACIB5 Large ribosomal subunit protein bL36 (Gene Name=rpmJ)

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