Structure of PDB 6zsa Chain 3 Binding Site BS01

Receptor Information
>6zsa Chain 3 (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTYFSARKGKRKTVKAVIDRFLRLHCGLWVRRKAGYKKKLWKKTPARKKR
LREFVFCNKTQSKLLDKMTTSFWKRRNWYVDDPYQKYHDRTNLKV
Ligand information
>6zsa Chain XA (length=1499) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
auccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuuggac
acuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguag
gccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaaa
ucccaaacauauaacugaacuccucacacccaauuggaccaaucuaucac
ccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccucc
gcauaagccugcgucagauaacaacugacaauuaacagcccaauaucuac
aaucaaccaacaagucauuauuacccucacugucaacccaacacaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuuacc
ccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagaggca
ccgccugcccagugacacauguuuaacggccgcgguacccuaaccgugca
aagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggcuc
cacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugccc
gugaagaggcgggcauaacacagcaagacgagaagacccuauggagcuuu
aauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguugg
ggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuuc
accagucaaagcgaaccucaauugauccaauaacuugaccaacggaacaa
guuacccuagggauaacagcgcaauccuauucuagaguccauaucaacaa
uaggguuuacgaccucgauguuggaucaggacaucccgauggugcagccg
cuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguu
cagaccggaguaauccaggucgguuucuaucuacuuauuccucccuguac
gaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccguaa
augauaucaucucaacuuagaauacccacacccacccaagaacaggguu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
.>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>
.<.<<<......>>>.>..<<<.<<<...<..............<....<
<<.........>>>....>.......<<<......>>>............
...............>...>>>>>>........>>>>>>...<<<<<...
...>>>>>.........>>>>>><......<<..<<<....>>><<<<..
<<<<........<<<<<.......>>>>>......<<<...<<<<.....
..................>>>>.......>>>.....<<......>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<<<
<<<..<<<.........>>>...<<<<<<.............>>>>>>..
..<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>..
......<...........<<<<<<.....>>>>>>.....>....>>>..
..>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<<<
<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<..
<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<..
...>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<..
...>>>>..>>>....>>.........<<<....>>>............>
>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>
>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>
>>>>>...>>.<<<<.......>>>>.....>>>>>..>...>>>.>>..
..<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<.......
..........>>>.>>><<<<<...<<<....>>>.>>>>>......<<<
................>>>..............<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB6zsa Structural basis of mitochondrial translation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		L94 T95 Y96 S98 A99 R100 K101 K103 R104 K105 T106 K108 R113 H118 R124 K126 A127 K131 K132 L133 W134 K135 R140 K142 R143 R145 K152 K156 K160 W166 R168 R169 D182
Binding residue
(residue number reindexed from 1)		L1 T2 Y3 S5 A6 R7 K8 K10 R11 K12 T13 K15 R20 H25 R31 K33 A34 K38 K39 L40 W41 K42 R47 K49 R50 R52 K59 K63 K67 W73 R75 R76 D89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zsa, PDBe:6zsa, PDBj:6zsa
PDBsum6zsa
PubMed32812867
UniProtQ9NZE8|RM35_HUMAN Large ribosomal subunit protein bL35m (Gene Name=MRPL35)

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