Structure of PDB 6u0m Chain 3 Binding Site BS01

Receptor Information
>6u0m Chain 3 (length=594) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNILPHRIIIS
LDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHHPWKLSFK
GSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGR
FHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITV
QEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQ
SNSNTLIGFKTLILGNTVYPLHAARQMLTDFDIRNINKLSKKKDIFDILS
QSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTA
KSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVL
ADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIA
AANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEH
VLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKK
SPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6u0m DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
A444 R455 K499
Binding residue
(residue number reindexed from 1)
A380 R391 K435
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0042555 MCM complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6u0m, PDBe:6u0m, PDBj:6u0m
PDBsum6u0m
PubMed
UniProtP24279|MCM3_YEAST DNA replication licensing factor MCM3 (Gene Name=MCM3)

[Back to BioLiP]