Structure of PDB 6raz Chain 3 Binding Site BS01

Receptor Information
>6raz Chain 3 (length=590) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EGEQFIKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKR
KNPQRALGLLSNAADEQLAFGRALKEYASTVDPGYAKMHEDLFVGFERHV
TPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTD
LTSFEAVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPLP
RSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGTFRTVLLANNISLLS
KELDISREDIMLCKKLAKNNDIFELLSKSLAPSIGHVKQAILCLLLGGVE
KILPNGTRLRGDINVLLGDPSAKSQLLRYVLNTAPRAIPTTGRGSSGVGL
TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQ
GRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSR
FDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEYEKYDALLHGKSRQRH
EKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVAR
TQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6raz Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Resolution4.46 Å
Binding residue
(original residue number in PDB)		A376 E382
Binding residue
(residue number reindexed from 1)		A353 E359
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
Biological Process
GO:0000727 double-strand break repair via break-induced replication
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006279 premeiotic DNA replication
GO:0032508 DNA duplex unwinding
GO:1902975 mitotic DNA replication initiation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0042555 MCM complex
GO:0071162 CMG complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6raz, PDBe:6raz, PDBj:6raz
PDBsum6raz
PubMed31484077
UniProtQ9XYU1|MCM3_DROME DNA replication licensing factor Mcm3 (Gene Name=Mcm3)

[Back to BioLiP]