Structure of PDB 6ray Chain 3 Binding Site BS01

Receptor Information
>6ray Chain 3 (length=600) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EGEQFIKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKR
KNPQRALGLLSNAADEQLAFGRALKEYASTVDPGYAKMHEDLFVGFRHVT
PRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDL
TSFEAVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQ
LPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGSGTFRTVLLANNI
SLLSKESLDISREDIMLCKKLAKNNDIFELLSKSLAPSIGHVKQAILCLL
LGGVEKILPNGTRLRGDINVLLGDPSAKSQLLRYVLNTAPRAIPTTGRGS
SGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIH
EVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQD
SLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEYEKYDALLHGK
SRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVE
TDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYF
Ligand information
Receptor-Ligand Complex Structure
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PDB6ray Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Resolution4.28 Å
Binding residue
(original residue number in PDB)		D380 E382
Binding residue
(residue number reindexed from 1)		D362 E364
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
Biological Process
GO:0000727 double-strand break repair via break-induced replication
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006279 premeiotic DNA replication
GO:0032508 DNA duplex unwinding
GO:1902975 mitotic DNA replication initiation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0042555 MCM complex
GO:0071162 CMG complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ray, PDBe:6ray, PDBj:6ray
PDBsum6ray
PubMed31484077
UniProtQ9XYU1|MCM3_DROME DNA replication licensing factor Mcm3 (Gene Name=Mcm3)

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