Structure of PDB 5tzs Chain 3 Binding Site BS01

Receptor Information
>5tzs Chain 3 (length=216) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKLNISYNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKI
SGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIV
GPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDD
VRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQR
EAAAEYAQLLAKRLSE
Ligand information
>5tzs Chain 1 (length=515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuc
auuaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaa
uucuagagcuaauacaugcuuguauuuauuaggaugauucauaauaacuu
uucgaaucgcauggccuugugcuggcgaugguucauucaaauuucugccc
uaucaacuuucgaugguaggauaguggccuaccaugguuucaacggguaa
cggggauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcguuacccaauccuaauucagggagguagugaaacgauac
agggccggucuuaauuggaaugaguacaauguaaauaccuuaacgagaag
ggcaccaccaggaguggagccugcggcgcgcgcuacacugacggagccag
cggaaacuccgucgugacgaggaauuccuaguaagcgcaagugcguugau
uacgucccugcccuu
..<<<..<<....<<....<<..........>>...>>.>>......<<.
.......<<<..<<..<<....<<<..........<.....<<.<<....
...>>.>>......>......<...<<<<<<.<......>.>>>>>>...
..>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<.....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>........<<<....<<<.....>>>..>>>.......<<<<<.
.<<<<<>>>>>>>.>>>......<<..<...........>..>>...<<<
<<<<..<<..<<<<<..<<<.<<<...>>>.>>>.....<<<<<<<....
......>>>>>>>..........>>>>>.....<<<<<<..>>>>>>...
...>>...>>>>>>>
Receptor-Ligand Complex Structure
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PDB5tzs Architecture of the yeast small subunit processome.
Resolution5.1 Å
Binding residue
(original residue number in PDB)
S6 S53 N56 K58 Q59 G60 P62 C83 Y84 A107 L133 G134 T170 P173 K174 T180 P181 R183 L184 R186 K187 R191 A192 L193 K194 V195 R196 N197 A198 Q199 A200 Q201
Binding residue
(residue number reindexed from 1)
S6 S51 N54 K56 Q57 G58 P60 C81 Y82 A105 L131 G132 T168 P171 K172 T178 P179 R181 L182 R184 K185 R189 A190 L191 K192 V193 R194 N195 A196 Q197 A198 Q199
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5tzs, PDBe:5tzs, PDBj:5tzs
PDBsum5tzs
PubMed27980088
UniProtP0CX37|RS6A_YEAST Small ribosomal subunit protein eS6A (Gene Name=RPS6A)

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