Structure of PDB 1c8m Chain 3 Binding Site BS01

Receptor Information
>1c8m Chain 3 (length=238) Species: 31708 (rhinovirus A16) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLPVYVTPGSGQFMTTDDMQSPCALPWYHPTKEIFIPGEVKNLIEMCQVD
TLIPINSTQSNIGNVSMYTVTLSPQTKLAEEIFAIKVDIASHPLATTLIG
EIASYFTHWTGSLRFSFMFCGTANTTLKVLLAYTPPGIGKPRSRKEAMLG
THVVWDVGLQSTVSLVVPWISASQYRFTTPDTYSSAGYITCWYQTNFVVP
PNTPNTAEMLCFVSGCKDFCLRMARDTDLHKQTGPITQ
Ligand information
>1c8m Chain 4 (length=29) Species: 31708 (rhinovirus A16) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAQVSRQSINYFNINYFKDAASSGASRLD
Receptor-Ligand Complex Structure
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PDB1c8m Structure of a Human Common Cold Virus and Functional Relationship to Other Picornaviruses
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D18 Q20 S21 C23
Binding residue
(residue number reindexed from 1)		D18 Q20 S21 C23
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1c8m, PDBe:1c8m, PDBj:1c8m
PDBsum1c8m
PubMed
UniProtQ82122|POLG_HRV16 Genome polyprotein

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