Structure of PDB 5hcq Chain 2l Binding Site BS01 |
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| >5hcq Chain 2a (length=1483)
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uuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaaga
caugcaagucgugcgggccgcgggguacuccguggucagcggcggacggg
ugaguaacgcgugggugaccuacccggaagagggggacaacccggggaaa
cucgggcuaaucccccauguggacccgccccuugggguguguccaaaggg
cuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggggu
aauggcccaccaaggcgacgacggguagccggucugagaggauggccggc
cacaggggcacugagacacgggccccacuccuacgggaggcagcaguuag
gaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggagga
agaagcccuucgggguguaaacuccugaacccgggacgaaacccccgacg
aggggacugacgguaccgggguaauagcgccggccaacuccgugccagca
gccgcgguaauacggagggcgcgagcguuacccggauucacugggcguaa
agggcguguaggcggccuggggcgucccaugugaaagaccacggcucaac
cgugggggagcgugggauacgcucaggcuagacggugggagaggguggug
gaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccgau
ggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgug
gggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugcg
cgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgc
cgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggggg
cccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaac
cuuaccaggccuugacaugcuagggaacccgggugaaagccugggccuag
cacaggugcugcauggccgucgucagcucgugccgugagguguuggguua
agucccgcaacgagcgcaacccccgccguuaguugccagcgguucggccg
ggcacucuaacgggacugcccgcgaaagcgggaggaaggaggggacgacg
ucuggucagcauggcccuuacggccugggcgacacacgugcuacaaugcc
cacuacaaagcgaugccacccggcaacggggagcuaaucgcaaaaaggug
ggcccaguucggauuggggucugcaacccgaccccaugaagccggaaucg
cuaguaaucgcggaucagccaugccgcggugaauacguucccgggccuug
uacacaccgcccgucacgccaugggagcgggcucuacccgaagucgccgg
gagccuacgggcaggcgccgaggguagggcccgugacuggggcggucgua
acaagguagcuguaccggaaggugcggcuggau |
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<
<.<<<..<<<..<<.<<<<<<<<<....>>>>>>>>>.>>>>>......<
<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<.....
.>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<
<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<..
.....>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>
.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>.
.......<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<..
....<<<<....>>>>.....>>>>....<<<<<......<.<<<<....
.>>>>..>.......>>>>>......<<<<<(((...<<<<<.....<<.
)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((..
...<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>
>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<.
...<<<<<<<.<..<<<......>>>.....>.>>>>>>>..........
.<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<
<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<
<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>
.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<
<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>......
....<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>>>>>>
>>..<<.<<<..<<<<<<.......<<<<<<<<<....>>>..<<<<...
...>>>>..>>>>>>.....<<<<.<<<<<<<..<<<..<<<.....>>>
>>>...>>>>>>>.....<<<<<....>>>>>........>>>>......
...>>>...>>>>>>>>....>>>>>>>...>>.>>>>>>>>.....<<<
<<<<.....<<<..<<..<<<<....>>>>..>>....>>>.....>>>>
>>>......<....<<<<<<<........>>>>>>>....>.....>>>>
>>....<<<<<<<..........>>>>>>>......>>...>>>>>>>>>
>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<...<.<<<<..
..<<<....>>>.>>>>.>..>>>>>>>>>>>>>..>>>.>>>>>.>>..
.>.....<<<<<<<<<....>>>>>>>>>.... |
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| PDB | 5hcq Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. |
| Resolution | 2.801 Å |
Binding residue
(original residue number in PDB) | P5 T6 N8 Q9 L10 R12 R15 E16 P31 F32 R33 R34 N49 S50 L52 R53 K54 T61 Y69 G72 E73 R86 G87 K91 D92 R97 R113 K114 K115 S116 R117 S118 K119 Y120 T122 K123 K124 |
Binding residue
(residue number reindexed from 1) | P1 T2 N4 Q5 L6 R8 R11 E12 P27 F28 R29 R30 N45 S46 L48 R49 K50 T57 Y65 G68 E69 R82 G83 K87 D88 R93 R109 K110 K111 S112 R113 S114 K115 Y116 T118 K119 K120 |
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| Enzyme Commision number |
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