Structure of PDB 9b00 Chain 2R Binding Site BS01 |
|
>9b00 Chain 2A (length=2800)
[Search RNA sequence]
[Download ligand structure]
[Download structure with residue number starting from 1]
[View ligand structure]
|
agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc ugcgcggggggaaccuggggaacugaaacaucucaguacccagaggagag gaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccagccu aaaccguccggcuuguccgggcggggucguggggcccucggacaccgaau ccccagccuagccgaagcuguugggaagcagcgccagagagggugaaagc cccguaggcgaaagguggggggauaggugaggguacccgaguaccccgug guucguggagccaugggggaaucugggcggaccaccgccuaaggcuaagu acuccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaaga accccgggaggggagugaaauagagccugaaaccgugggcuuacaagcag ucacggccccggggguuguggcgugccuauugaagcaugagccggcgacu cacggucgugggcgagcuuaagccguugaggcggaggcguagggaaaccg aguccgaacagggcgcaagcgcgcaaaguccgcggccguggacccgaaac cgggcgagcuagcccuggccagggugaagcuggggugagacccaguggag gcccgaaccggugggggaugcaaaccccucggaugagcuggggcuaggag ugaaaagcuaaccgagcccggagauagcugguucuccccgaaaugacuuu agggucagccucaggcgcugacuggggccuguagagcacugauagggcua gggggcccaccagccuaccaaacccugucaaacuccgaagggucccaggu ggagccugggagugagggcgcgagcgauaacguccgcguccgagcgcggg aacaaccgagaccgccagcuaaggcccccaagucugggcuaagugguaaa ggauguggcgccgcguggcgccgcgccgaaaaugaucggggcuuaagccc agcgccgaagcugcgggucuggggccccaggcgguaggggagcguucccg augccgaugaaggccgacccgcgagggcggcuggagguaagggaagugcg aaugccggcaugaguaacgauaaagagggugagaaucccucucgccguaa gcccaaggguuccuacgcaauggucgucagcguaggguuaggcgggaccu aaggugaagccgaaaggcguagccgaagggcagccgguuaauauuccggc ccuucccgcaggugcgauggggggacgcucuaggcuagggggaccggagc cauggacgagcccggccagaagcgcagggugggagguaggcaaauccgcc ucccaacaagcucugcgugguggggaagcccgcgggugacaaccccccga agccagggagccaagaaaagccucuaagcacaaccugcgggaacccguac cgcaaaccgacacaggugggcgggugcaagagcacucaggcgcgcgggag aacccucgccaaggaacucugcaaguuggccccguaacuucgggagaagg ggugcucccuggggugaugagccccggggagccgcagugaacaggcucug gcgacuguuuaccaaaaacacagcucucugcgaacucguaagaggaggua uagggagcgacgcuugcccggugccggaaggucaaggggaggggugcaag ccccgaaccgaagccccggugaacggcggccguaacuauaacgguccuaa gguagcgaaauuccuugucggguaaguuccgaccugcacgaaaagcguaa cgaccggagcgcugucucggcgagggacccggugaaauugaacuggccgu gaagaugcggccuacccguggcaggacgaaaagaccccguggagcuuuac ugcagccugguguuggcucuuggucgcgccugcguaggauaggugggagc cugugaacccccgccuccgggugggggggaggcgccggugaaauaccacc cuggcgcggcugggggccuaacccucggauggggggacagcgcuuggcgg gcaguuugacuggggcggucgccuccuaaaagguaacggaggcgcccaaa gguccccucaggcgggacggaaauccgccggagagcgcaaggguagaagg gggccugacugcgaggccugcaagccgagcaggggcgaaagccgggccua gugaaccgguggucccguguggaagggccaucgaucaacggauaaaaguu accccggggauaacaggcugaucucccccgagcguccacagcggcgggga gguuuggcaccucgaugucggcucgucgcauccuggggcugaagaagguc ccaaggguugggcuguucgcccauuaaagcggcacgcgagcuggguucag aacgucgugagacaguucggucucuauccgccacgggcgcaggaggcuug aggggggcucuuccuaguacgagaggaccggaagggacgcaccucugguu ucccagcugucccuccaggggcauaagcuggguagccaugugcggaaggg auaaccgcugaaagcaucuaagcgggaagcccgccccaagaugaggccuc ccggcagccgguaaggacccgggaagaccacccgguggaugggccggggg uguaagcgccgcgaggcguugagccgaccggucccaaucguccgaggucu |
<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<< <<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>> >>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<< .>>>>>>.>>...<<<<<<.....<......>......>>>>>.>..... ....<<....>>...<<<<<.....<<.....>>....>>>>>...<<<. ...<<<<<<<<.....>>>>>>>>......<<<<<<<<<<....<<...< <<<<.<<<<.<<<...<<<<<......>>>>>((......<<<.....)) >>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<<<<<< <<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>..... .>>.>>>>>>.>>...............<<....>>....>>........ .<<<<....>>>>..................>>>>>>>>>>>.......< <<<<<<<<<<.>>>>>>>>>>>...<............>.<<<<<<.... <<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<....>>. .<<<<.....>>>>....<<..>>...>>>>>>>>>>>>>..<<.<...< <<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>.... .>>>...<<<<.<<<<........>>>>>>>>....>>>>>>>>>...<< <.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<.. ..>>>>><<<<<<<<<.....<<<<<<<<<...<<<...<<<<<<<<... .<<<..........>>.>....>>>>>>>>..>>.>...>>>>>>>>>.. ...>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>.....<<<. .....>>>...<<<<.<<<...<<<(((.....<<<<<<........... <<..<<<<<<<<<..>>>>>>>>>.>>..........)))......>>>> >>.>>>...>>>>>>><<<<<<<<>>>>>>>>....>>>>>>..<<<<<. ..<<<......<<<<<.<<<....>>>>>>>>...>>>..>>>>>..... ...>>>>>><......<<.....<<<<<<.......>>>>>><<<<.... <<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<. ..<<<...<<<....>>>...>>>...>>...<<<<<........>>>>> ))<<<<<<<<<<<<<...<<<<....<<<<<.<<<..<<<<<.<<<<.<< ..[[[[...>>>>>><<<...<<<<<<<<<<<<<<<<.<<.....>>>>> >>>>.....>>>>>>>>>..>>><...<<<<..>>>>.....>>>>>>.. .>>>..>>>>>.........>>>>...>>...>>>>>>>>>>>>>>>..> >.....<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<.. ..<<<<<<<<.<<.........<.....<<<<<.....<..>......>> >>><<<<<<<<<<<<.....>>>>>>>>>>>>............<<<<<< <<<..<<<.........>>>..<<<<<<<.....<<<....>>>...... .>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<....> >>>>...>>...>>>>>>>>..>>>>><<<<<<.......>>>>>>.... ....<...........<<<<<<.....>>>>>>.....>....>>>>>.. >>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<. .......>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<< <<<.<<<.<<<<<.<<<<<<<<<<<<<<<<...........<<<<<..<< <......<<<<<<<<....>>>>>>>>...>>>............>>>>> ..>>>>>>>>>>>>>>>>...<<<<<....>>>>>....>>>>>.>>>.. >>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<... <<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>> >>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>))). ......<<<<<<<.<<..))))..>>>>>>>>>.............>>>> ..>>>>>>.......<<<<...<<<<<<...<<.......>>...>>>>> >....>>>.>.......<<<<<..<<<<<..<<<<<<<<<......>>>> >>>..>>.<<<<<.....>>>>>.....>>>>>......>>>.>>....< <<<<<<....>>>.>>>>........>>>>>>>>>>>....<<<<<<<.. .<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<. ..<<<<<<<<<<<]]]]>>>>>>...>>>>>...>>>>.>>>>>...<<< ....<<<<<...........>>>>>....>>>.>>>>.......>>>>>> >.<<...>>.....<<<<<<<<<.......>>>>>....<<<<<<<<.<< <....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>> |
|
Global view | Local view | Structure summary |
[Spin on]
[Spin off]
[Reset]
[High quality]
[Low quality]
[White background]
[Black background]
|
[Spin on]
[Spin off]
[Reset]
[High quality]
[Low quality]
[White background]
[Black background]
|
PDB | 9b00 Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity. |
Resolution | 2.8 Å |
Binding residue (original residue number in PDB) | M1 R2 H3 L4 K5 S6 R8 K9 N11 R12 H13 S14 S15 H16 R17 L20 R22 N23 Q24 S27 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 H61 R63 R64 L67 R68 Q71 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 |
Binding residue (residue number reindexed from 1) | M1 R2 H3 L4 K5 S6 R8 K9 N11 R12 H13 S14 S15 H16 R17 L20 R22 N23 Q24 S27 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 H61 R63 R64 L67 R68 Q71 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 |
|
|
|