Structure of PDB 6ip6 Chain 2I Binding Site BS01 |
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>6ip6 Chain 1A (length=3667)
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cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc agcggaggagaagaaacuaaccaggauucccucaguaacggcgagugaac agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggacau guggcguacggaagacccgcuccccggcgccgcucguggggggcccaagu ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg caguccgcccggaggauucaacccggcggcggguccggccgugucggcgg cccggcggaucuuucccgcgcgggggaccgucccccgaccggcgaccggc cgccgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccggg acggcugggaaggcccggcggggaagguggcucgggggcccccgaguguu acagcccccccggcagcagcacucgccgaaucccggggccgagggagcga gacccgucgccgcgcucuccccccucccggcgcgccggggggggccgggc caccccucccacggcgcgaccgcucggggcggacuguccccagugcgccc cgggcgggucgcgccgucgggcccgggggaggccacgcgcgcgucccccg aagagggggacggcggagcgagcgcacggggucggcggcgacgucggcua cccacccgacccgucuugaaacacggaccaaggagucuaacacgugcgcg agucgggggcucgcacgaaagccgccguggcgcaaugaaggugaaggccg gcgcgcucgccggccgaggugggaucccgaggccucuccaguccgccgag ggcgcaccaccggcccgucucgcccgccgcgccggggagguggagcacga gcgcacguguuaggacccgaaagauggugaacuaugccugggcagggcga agccagaggaaacucugguggagguccguagcgguccugacgugcaaauc ggucguccgaccuggguauaggggcgaaagacuaaucgaaccaucuagua gcugguucccuccgaaguuucccucaggauagcuggcgcucucgcagacc cgacgcccgccacgcaguuuuauccgguaaagcgaaugauuagaggucuu ggggccgaaacgaucucaaccuauucucaaacuuuaaauggguaagaagc ccggcucgcuggcguggagccgggcguggaaugcgagugccuagugggcc acuuuugguaagcagaacuggcgcugcgggaugaaccgaacgccggguua aggcgcccgaugccgacgcucaucagaccccagaaaagguguugguugau auagacagcaggacgguggccauggaagucggaauccgcuaaggagugug uaacaacucaccugccgaaucaacuagcccugaaaauggauggcgcugga gcgucgggcccauacccggccgucgccggcagucgagaguggacgggagc ggcggcccggagccccgcggacgcuacgccgcgacgaguaggagggccgc ugcggugagccuugaagccuagggcgcgggcccggguggagccgccgcag gugcagaucuuggugguaguagcaaauauucaaacgagaacuuugaaggc cgaaguggagaaggguuccaugugaacagcaguugaacaugggucagucg guccugagagaugggcgagcgccguuccgaagggacgggcgauggccucc guugcccucggccgaucgaaagggagucggguucagauccccgaauccgg aguggcggagaugggcgccgcgaggcguccagugcgguaacgcgaccgau cccggagaagccggcgggagccccggggagaguucucuuuucuuugugaa gggcagggcgcccuggaauggguucgccccgagagaggggcccgugccuu ggaaagcgucgcgguuccggcggcguccggugagcucucgcuggcccuug aaaauccgggggagaggguguaaaucucgcgccgggccguacccauaucc gcagcaggucuccaaggugaacagccucuggcauguuggaacaauguagg uaagggaagucggcaagccggauccguaacuucgggauaaggauuggcuc uaagggcugggucggucgucggccggcgccuagcagccgacuuagaacug gugcggaccaggggaauccgacuguuuaauuaaaacaaagcaucgcgaag gcccgcggcggguguugacgcgaugugauuucugcccagugcucugaaug ucaaagugaagaaauucaaugaagcgcggguaaacggcgggaguaacuau gacucucuuaagguagccaaaugccucgucaucuaauuagugacgcgcau gaauggaugaacgagauucccacugucccuaccuacuauccagcgaaacc acagccaagggaacgggcuuggcggaaucagcggggaaagaagacccugu ugagcuugacucuagucuggcacggugaagagacaugagugaucguuuuu ucacugacccggugaggcgggggggcgagccccgaggggcucucgcuucu ggcgccaagcgcccggccgcgcgccggccgggcgcgacccgcuccgggga cagugccagguggggaguuugacuggggcgguacaccugucaaacgguaa cgcagguguccuaaggcgagcucagggaggacagaaaccucccguggagc agaagggcaaaagcucgcuugaucuugauuuucaguacgaauacagaccg ugaaagcggggccucacgauccuucugaccuuuuggguuuuaagcaggag gugucagaaaaguuaccacagggauaacuggcuuguggcggccaagcguu cauagcgacgucgcuuuuugauccuucgaugucggcucuuccuaucauug ugaagcagaauucaccaagcguuggauuguucacccacuaauagggaacg ugagcuggguuuagaccgucgugagacagguuaguuuuacccuacugaug auguguuguugccaugguaauccugcucaguacgagaggaaccgcagguu cagacauuugguguaugugcuuggcugaggagccaauggggcgaagcuac caucugugggauuaugacugaacgccucuaagucagaaucccgcccaggc ggaacgauacggcagcgccgcggagccucgguuggccucggauagccggu cccccgcgggguccggugcggagugcccuucguccugggaaacggggcgc ggccggagaggcggccgcccccucgcccgucacgcaccgcacguucgugg ggaaccuggcgcuaaaccauucguagacgaccugcuucugggucgggguu ucguacguagcagagcagcucccucgcugcgaucuauugaaagucagccc ucgacacaaggguuugu |
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PDB | 6ip6 HCV IRES Captures an Actively Translating 80S Ribosome. |
Resolution | 4.5 Å |
Binding residue (original residue number in PDB) | V4 R12 G17 R18 A21 K25 R37 S44 Y48 R49 K60 R61 M62 N63 N65 P66 R68 P70 Y71 H72 F73 R74 R82 T83 R85 M87 P89 H90 K91 K93 R94 Q96 F105 I108 P109 P110 P111 K114 K115 K116 R117 V126 R128 L129 K130 R133 K134 E144 V145 K148 Y149 L156 K161 A164 K165 Y168 R169 K171 K172 M175 R176 K188 V203 |
Binding residue (residue number reindexed from 1) | V2 R10 G15 R16 A19 K23 R35 S42 Y46 R47 K58 R59 M60 N61 N63 P64 R66 P68 Y69 H70 F71 R72 R80 T81 R83 M85 P87 H88 K89 K91 R92 Q94 F103 I106 P107 P108 P109 K112 K113 K114 R115 V124 R126 L127 K128 R131 K132 E142 V143 K146 Y147 L154 K159 A162 K163 Y166 R167 K169 K170 M173 R174 K186 V201 |
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Enzyme Commision number |
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