Structure of PDB 5fki Chain 2C Binding Site BS01

Receptor Information
>5fki Chain 2C (length=245) Species: 10345 (Suid alphaherpesvirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIADVGTDRYAPYFAYAAAQPSDEVTTVRGLSNPLIKTAPVTLPFDLGQA
VADNCLSLSGMGYYLGLGGCCPTCAAAEPRLGRSDRAALVLAYVQQLNSI
YEYRVFLASVAARDPSERALEEVLAHPELFFAYYVLRDGRDVRVLFFEDP
DAQGALMMYVVFPEKSVHVHHRVLDRLLGACAGHRIVAHVWQTMFVLVVR
KKGDDVPAVSASDIYCKMRDISFDGELLLEYKRLYAAFEDFRPPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5fki Chain 2C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5fki Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights Into Inner Nuclear Membrane Remodelling
Resolution35.0 Å
Binding residue
(original residue number in PDB)		C73 C89 C92
Binding residue
(residue number reindexed from 1)		C55 C71 C74
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

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Molecular Function
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Biological Process
External links
PDB RCSB:5fki, PDBe:5fki, PDBj:5fki
PDBsum5fki
PubMed26711332
UniProtG3G955

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