Structure of PDB 5mrc Chain 22 Binding Site BS01

Receptor Information

>5mrc Chain 22 (length=99) Species: 4932 (Saccharomyces cerevisiae)

TIPKPSDQVPDVDAFLNKIGRNCNELKDTFENNWNNLFQWDSKILKEKGV
NIQQRKYILKQVHNYRNNRPIHEIKLGKKSFFGGERKRKAFTAKWKAEN

Ligand information

>5mrc Chain aa (length=1501)

uaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacaca
ugcgaaucauacguuuauuauugagauaauaaauaugugguguaaacgug
aguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacuuaau
auuauauaaaaaauuuauauaauaaaaaggauauauauauauauauuuau
cuauagucaagccaauaaugguuuagguaguagguuuauuaagaguuaaa
ccuagccaacgauccauaaucgauaaugaaaguuagaacgaucacguuga
cucugaaauauagucaauaucuauaagauacagcagugaggaauauugga
caaugaucgaaagauugauccaguuacuuauuaggaugauauauauauau
auauaaauugauuaaaaauaaaauccauaaauaauuaaaauaaugauauu
aauuaccauauauuuauauggauauauauauauuuuaauaguccugacua
auauuugugccagcagucgcgguaacacaaagagggcgagcguuaaucau
aaugguuuaaaggauccguagaaugaauuauauauaauuuagaguuaaua
aaauuaauuaaagaauuauaauaguaaagaugaaauaauaauaauaauua
uaagacuaauauaugugaaaauauuaauuaaauauuaacugacauugagg
gauuaaaacuagaguagcgaaacggauucgauacccguguaguucuagua
guaaacuaugaauacaauuauuuauaauauauauauaaauaauaaaugaa
aaugaaaguauuccaccugaagaguacguuagcaauaaugaaacucaaaa
caauagacgguuacagacuuaagcaguggagcauguuauuuaauucgaua
auccacgacuaaccuuaccauauuuugaauauuauaauaauuauaauuau
uauauuacaggcguuacauuguugucuuuaguucgugcugcaaaguuuua
gauuaaguucauaaacgaacaaaacuccauauauauaauuuuaauuauau
auaauuuuauauuauuuaauauaaagaaaggaauuaagacaaaucauaau
gauccuuauaauauggguaauagacgugcuauaauaaaaugauaauaaaa
uuauauaaaauauauuuaauuauauuuaauuaauaauauaaaacauuuua
auuuuuaauauauuuuuuuauuauaaauaugaauuauaaucugaaauucg
auuauaugaaaaaagaauugcuaguaauacguaaauuaguauguuacggu
gaauauucuaacuguuucgcacuaaucacucaucacgcguugaaacauau
uauuaucuuauuauuuauauaauauuuuuuaauaaauauuauuaauuuau
auuuauuuauaucagaaauaauaugaauuaaugcgaaguugaaauacagu
uaccguaggggaaccugcggugggcuuauaaauaucuuaaauauucuuac
a

...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<......<<<.
<<<..<<<..<<<<<<<<<<<<..>>>>>>>>>>..>>>>>.....<<<.
.......<<<<<.<<.........<<<<<<<<.<<<<.......>>>>..
.<<<<<<<<<...>>>>>>>>>......<<<<<<<<<..>>>>>>>>>.>
>>>>>>>....>>>>>>><<<....<<<..<<<<<<<<........>>>>
>>>>>>>......>>>..<<<<.<<<<....>>>>...>>>>.>>><<<<
<<.........>>>>>><<<<.....>>>>..>>>>>>.........<<<
....<<<<....>>>>..>>>...>.>>>>>>.<<<<..<<<<<<....>
>>>>>..<<......>>.....>>>>..<<<<<<<<..............
>>>>><<<<<<<..>>>>>>><<<<<..>>>>>>>>....<<<<<(((..
...<<<<.....<<.)))>>.......>>>>.>>>>>..>>>>>>>>>..
...<<<((.....<<<<...<.<<.<<<<<<..>>>>>>...<<<<<<<<
...<<<<<<<<<<..<<<<<<<........................>>>>
>>>..>>.......<<....>>.>>>>>>>>.>>>>>>>>...>>>...>
>>>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>.
.........<<<<<<.<<<<<<<<<<.<..>..>>>>>>>>>>..<<..)
)>>....>>>>>>.>>>.<<.......<<<<....>>>>.....>>..))
)).]<<.<<...<<<<.....<<<<<<..<<<<<<<<<<......<<...
.....>>..........<<<<<<<.....<<.<<<<<<<<<<..>>>>>>
>>>>.>>.<<<.<<<..<<<<<<<<<....<<<<<<<<<....>>>....
<<......>>....>>>>>>.....<<<.<<<<<<<<........>>>>>
>>>..<<<<<<<<<..>>>>>>>>>....>>>.....>>>.>>>...>>>
>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<........<
<<..<<..<<<<<<......>>>>>>..>>....>>>......>>>>>>.
.....<<<<<........>>>>>......<....<<<<<<<........>
>>>>>>....>.....>>>>>>....<<.<<<<<.........>>>>>>>
...........>>>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<
<<<<.<<<...<<<..<<<.<<<<<...<<<<<<<...>>>>>>>...>>
>>>>>>..>>>..>>>>>>>>>>>>..>>>>>>>>..>.>>>..>.....
<<<<<<<<<....>>>>>>>>>............................
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5mrc The structure of the yeast mitochondrial ribosome.
• Resolution: 3.25 Å
• Binding residue (original residue number in PDB): R50 K75 I81 Q82 K85 H92 I103 K104 G106 K107 K108 S109 F110 F111 G113 E114 R115 K118 A119 A122 W124 A126
• Binding residue (residue number reindexed from 1): R21 K46 I52 Q53 K56 H63 I74 K75 G77 K78 K79 S80 F81 F82 G84 E85 R86 K89 A90 A93 W95 A97

External links

• PDB: RCSB:5mrc, PDBe:5mrc, PDBj:5mrc
• PDBsum: 5mrc
• PubMed: 28154081
• UniProt: P38783|FYV4_YEAST Small ribosomal subunit protein mS41 (Gene Name=FYV4)