Structure of PDB 8fn6 Chain 2 Binding Site BS01

Receptor Information
>8fn6 Chain 2 (length=428) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFSHITRNTVWGLWNEGNLFSLSVPELAFFLQEHCRVANVDPRAKKSALV
RQVEEILSAEQQASATVPQEDNPHAIVVTDYEEADEYGDWGAEPGFEDRR
ELDFMELSPRYDPLSPRAFQLLHSETATDVGIASIDPSKLPGQSKVKNAL
AAIHVAPNDANKMRFRMAFEWCLMNIWNMNMPGELNIGAGKALYYRSVAK
QNRNVMPLWTVQKHLYAQHPYAWFAIASESNVAAMESLAAALNMSIQQER
TTSYKVTIRRMAEFFDCELNGQLKCTMMNKPWDRFFVSHYIRSKMPDLRY
VVRARHPIKKRIADAYLEADILRSTRDSVQSVLSPELGDVVYCCERVVRK
WAKKTATGVTLQLVETKRTPLIITKAGDEGERLEYEWIVPLPQQAERIDI
AALTDELWEYGNKLAAALEEGMEELMVH
Ligand information
>8fn6 Chain g (length=46) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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....<.<<<<<<<<<<<<<<<<..>>>>>>>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB8fn6 Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
L170 P172 H275 A278 W279 R340
Binding residue
(residue number reindexed from 1)
L114 P116 H219 A222 W223 R284
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0043489 RNA stabilization

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Molecular Function

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Biological Process
External links
PDB RCSB:8fn6, PDBe:8fn6, PDBj:8fn6
PDBsum8fn6
PubMed37410820
UniProtB6SBL9

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