Structure of PDB 8c9a Chain 2 Binding Site BS01

Receptor Information
>8c9a Chain 2 (length=35) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
Ligand information
>8c9a Chain A (length=650) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcuaa
ucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauuu
ccgaauggggaaacccaguguguuucgacacacuaucauuaacugaaucc
auagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccgag
gaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggagc
agcccagagccugaaucaguguguguguuaguggaagcgucuggaaaggc
gcgcgauacagggugacagccccguacacaaaaaugcacaugcugugagc
ucgaugaguagggcgggacacgugguauccugucugaauauggggggacc
auccuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgu
gagggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaa
accguguacguacuuauauucuguagcaagguuaaccgaauaggggagcc
gaagggaaaccgaaguugcaggguauuuccuguccaacguuaaucggggc
agggugagucgaaacagguuaauauuccuguacuugguaucaaaucguac
.<<<<<<<<<<....<<<..<<<<<<<<<<<<<......<<<<<<.[..(
((.>>>.....<<<<<<<..<<<)))..].>>>......>>>>>>>...>
>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<......
...>>>>>>>>>.>>...<<<<<<...................>>>>>.>
...................<<<<<......<<.....>>.....>>>>>.
.<<<..<<<<......<<<<<<<<<<<<<.<<<...<<<<<......>>>
>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>...>>
>>........<<<.<<<<.........>>>>.>>>......<<<<<....
.>>>.>>..>>>......>>.>>>>>>>.>>...............<<..
..>>....>>.........<<<<.....>>>>.............>....
>>>>>>>>>>.....<<<<<<<<<<<<...<....<<.....>>....>.
...<<....>>...>>>>>>>>>>>>..<<<<<<...<<.....>>.>>>
>>>....<<(...<<<<<........>>>>>>><<<<..>>>>...)...
Receptor-Ligand Complex Structure
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PDB8c9a Cryo-EM captures early ribosome assembly in action.
Resolution4.86 Å
Binding residue
(original residue number in PDB)		R12 N13 R14 H16 F18 R19 R21 M22 V30 R33 R34 R35 K37 G38 R39 A40 L42
Binding residue
(residue number reindexed from 1)		R3 N4 R5 H7 F9 R10 R12 M13 V21 R24 R25 R26 K28 G29 R30 A31 L33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c9a, PDBe:8c9a, PDBj:8c9a
PDBsum8c9a
PubMed36797249
UniProtP0A7P5|RL34_ECOLI Large ribosomal subunit protein bL34 (Gene Name=rpmH)

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