Structure of PDB 8c98 Chain 2 Binding Site BS01

Receptor Information
>8c98 Chain 2 (length=35) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
Ligand information
>8c98 Chain A (length=1018) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcua
aucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauu
uccgaauggggaaacccaguguguuucgacacacuaucauuaacugaauc
cauagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccga
ggaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggag
cagcccagagccugaaucaguguguguguuaguggaagcgucuggaaagg
cgcgcgauacagggugacagccccguacacaaaaaugcacaugcugugag
cucgaugaguagggcgggacacgugguauccugucugaauaugggggauc
cuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgugag
ggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaacc
guguacguacaagcagugggagcacgcuuaggcgugugacugcggucagc
gacuuauauucuguagcaagguuaaccgaauaggggagccgaagggaaac
cgagucuuaacugggcguuaaguugcaggguauagacccgaaacccggug
aaccgggagauagcugguucuccccgaaagcuauuuagguagcgccucgu
gaauucaucuccgggggagaauguuaucacgggagacacacggcgggugc
uaacguccgucgugaagagggaaacaacccagaccgccagcuaagguccc
aaagucaugguuaagggggcuaaaccaugcaccgaagcugcggcagcgac
gcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggugug
cugugaggcaugcuggagguaucagaagugcgaaugcugacuuccugucc
aacguuaaucggggcagggugagucgaaacagguuaauauuccuguacuu
ggugaucaaaucguaccc
.<<<<<<<<<<<....<<<..<<<<<<<<<<<<<......<<<<<<....
(((.>>>.....<<<<<<<..<<<)))....>>>......>>>>>>>...
>>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<.....
....>>>>>>>>>.>>...<<<<<<...................>>>>>.
>.........<<....>>..<<<<<<.....<<.....>>....>>>>>>
..<<<..<<<<......<<<<.<<<<<<<<.<<<...<<<<<......>>
>>>((......<<<.....))>>>...>>>...>>>>>>>>.>>>>...>
>>>........<<<.<<<<.........>>>>.>>>......<<<<<..>
>>>>..>>>......>>.>>>>>>>.>>...............<<....>
>....>>.........<<<<.....>>>>.............>....>>>
>>>>>>>>.......<<<<..<<<<<<....>>>>>>..>>>>.<<<<<<
....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<....>
>..<<<......>.>>.....>>>>>>>>>>>>>..<<.<..<<<<<<<.
.>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<
<<...<<<<<<<...>>>>>.>>...>>>>>>>.>...<<<<<<<<....
......>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((
.....<<<<<<....))).....>>>>>>.>>>...>>>>>>><<<<<<<
<<....>>>>>>>>>....>>>>>><<<<<<<...<<<......<<<<<<
<<....>>>>>>>>...>>>..>>>>>.>>.....>>>>>>..<<<<<<.
..<<.....>>.>>>>>>....<<((..<<<<<........>>>>>>><<
<<<.>>>>>..)).....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8c98 Cryo-EM captures early ribosome assembly in action.
Resolution3.66 Å
Binding residue
(original residue number in PDB)		L10 R12 R14 H16 F18 R19 N26 R33 R34 R35 K37 G38 R39 A40 R41
Binding residue
(residue number reindexed from 1)		L1 R3 R5 H7 F9 R10 N17 R24 R25 R26 K28 G29 R30 A31 R32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c98, PDBe:8c98, PDBj:8c98
PDBsum8c98
PubMed36797249
UniProtP0A7P5|RL34_ECOLI Large ribosomal subunit protein bL34 (Gene Name=rpmH)

[Back to BioLiP]