Structure of PDB 8c93 Chain 2 Binding Site BS01

Receptor Information
>8c93 Chain 2 (length=37) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
Ligand information
>8c93 Chain A (length=1740) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagugcguuaaguug
caggguauagacccgaaacccggugaccgggagauagcugguucuccccg
aaagcuauuuagguagcgccucgugaauucaucuccggggguagagcacc
aaacugcgaauaccggagaauguuaucacgggagacacacggcgggugcu
aacguccgucgugaagagggaaacaacccagaccgccagcuaagguccca
aagucaugguuaagugggaaacgcggaagauguaacggggcuaaaccaug
caccgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguu
cuguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagu
gcgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccg
gaagaccaaggguuccuguccaacguuaaucggggcagggugagucgacc
ccuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauucc
uguacuugguguuacugcgaaggggggacggagaaggcuauguuggccgg
gcgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaaucc
ggaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaa
caaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaau
cguaccccaaaccgacacagguggucagguagagaauaccaaggcgcuug
agaaauugaacucgcugugaagaugcaguguacccgcggcaagacggccu
aucugccgugggcgcuggagaacugaggggggcugcuccuaguacgagag
gaccggaguggacgcaucacugguguucggguugucaugccaauggcacu
gcccgguagcuaaaugcggaagagauaagugcugaaagcaucuaagcacg
aaacuugccccgagaugaguucucccugacccuuuaaggguccugaagga
acguugaagacgacgacguugauaggccggguguguaagcgcagcgaugc
guugagcuaaccgguacuaaugaaccgugaggcuuaaccu
<<<<<<<<......<<<<<<<<<<<....<<<..<<<<<<<<<<<<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>...<<<<<.....<<....
.>>....>>>>>...<<<..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<<....>>>>>>..>>>......>>.>>>>>>>.>>.....
..........<<....>>....>>.........<<<<.....>>>>....
.........>....>>>>>>>>>>>.......<<<<..<<<<<......>
>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>....<<...>>..<..>.....>>>>
>>>>>>>>>..<<.<..<<<<<<<.>>>>>>...>..>.>>..<<<<<<.
...<<<<<....>>>>>.<<<<<<<<...<<<<<<<<<.....<<<....
...>>.>.....>>>>>>.>>>...>>>>>>>.>...<<<<<<<<<<...
...>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.
....<<<<<<...........<<>>...........))).....>>>>>>
.>>>...>>>>>>><<<<<<<<<....>>>>>>>>>....>>>>>><<<<
<<<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>.>
>.....>>>>>>..............<<<<<<.......>>>>>><<<<.
...<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<
<<...<<....<<<....>>>....>>...>>>..<<<<<........>>
>>>))<<<<<<<<<<<.<..<<<<<....<<<<..<<<..<<<<<<<<<<
<....(((...>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>
>>>>>>>>..>>>>...>>>>...>><..<<<<<....>>>>>...>>>>
>>...>>>...>>>>.........>>>>>..>.....>>>>>>>>>>>.>
>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>....
............<<<<<........>>>>>..<<<<<<<<.<<<.<..>.
.>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...........
....>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))).>>>>>>..
>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>.
...>>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<.
.<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>
>>...>>...>>>>>.>>>.....>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB8c93 Cryo-EM captures early ribosome assembly in action.
Resolution4.17 Å
Binding residue
(original residue number in PDB)		L10 R12 N13 H16 F18 R19 N26 A32 R34 R35 K37 G38 R39 A40 R41
Binding residue
(residue number reindexed from 1)		L3 R5 N6 H9 F11 R12 N19 A25 R27 R28 K30 G31 R32 A33 R34
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c93, PDBe:8c93, PDBj:8c93
PDBsum8c93
PubMed36797249
UniProtP0A7P5|RL34_ECOLI Large ribosomal subunit protein bL34 (Gene Name=rpmH)

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