Structure of PDB 7of0 Chain 2 Binding Site BS01

Receptor Information
>7of0 Chain 2 (length=45) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARGNEYQPSNIKRKNKHGWVRRLSTPAGVQVILRRMLKGRKSLSH
Ligand information
>7of0 Chain A (length=1376) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccagacaaccuuagccaaa
ccauuuacccaaauaaaguauaggcgauagaaauugaaauggcgcaauag
auauaguaccgcaagggaaagacaagcauaauauagcaaggacuaacccc
uauaccuucugcaaugaauuaacuagaaauaacuuugcaaggagagccaa
agcuaagacccccgaaaccagacgagcuaccuaagaacagcuaaaagagc
acacccgucuauguagcaaaauagugggaagauuuauagguagaggcgac
aaaccuaccgagccuggugauagcugguuguccaagauagaaucuuaguu
caacuuuaaauuugcccacagaacccaaauccccuuguaaauuuaacugu
uaguccaaagaggaacagcucuuuggacacuaggaaaaaaccuuguagag
agaguaaaaaauuuaacacccauaguaggccuaaaagcagccaccaauua
agaaagcguucaagcucaacacaaaaaucccaaacauauaacugaacucc
ucacacccaauuggaccaaucuaucacccuauagaagaacuaauguuagu
auaaguaacaugaaaacauucuccuccgcauaagccugcgucagauacug
acaauuaacagcccaauaucuacaaucaaccaacaagucauuauuacccu
cacugucaacccaacacaggcaugcucauaaggaaagguuaaaaaaagua
aaaggaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccuc
uagcaucaccaguauuagaggcaccgccuuccuuaaauagggauggcucc
acgaggguucagcugucucuuacuuuuaaccagugaaauugaccugcccg
ugagaggcgggcauaacacagcaagacgagagacccuauggagcuuuaau
uuauuaaugcaaacaaccugcauuaaaaauuucgguuggggcgaccucgg
agcagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaag
cgaaccuuugauccaauaacuugaccaacggaacaaguuacccuagggaa
auccuauucuagaguccauaucaacaauaggguuuacgaccucguuggau
caggacaucccgauggugcagccgcuauuaaagguucguuuguucaacga
uuaaaguccuacgugaucugaguucagaccggaguaauccaggucgguuu
cuaucuacuuuaauuccucccuguacgaaaggacaagagaaauaaggccu
acuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauu
auacccacacacccaagaacaggguu
<<<.......<<<<.................................<..
....>...............<<.....>>...........>>.>>.....
........<<....>>........>>>...........<<<.......>>
>...<.<<....>>.>.<<<<<<.........<<<.<<..<<....>>..
.>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<.....>>>
...<<<..<<<<........>>>>.>>>....>>>.>>>>>...<<....
...>>......>.>>>>......>.>>..<<<<<<....<<<<....>>>
><<<.<<<<<<<<<<.....<<.......>>.....>>>>>>>>>>..>>
>.<<<<<<<<<<......>>>>>>>>>>...<<<......>>>....<<<
.<<<...<..............<....<<<.........>>>....>...
....<<<......>>>..........................>...>>>>
>>........>>>>>>...<<<<<......>>>>>.........>>>>>>
.......<<..<<<....>>><<<<..<<<<........<<<<<...>>>
>>......<<<...<<<<.......................>>>>.....
..>>>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<
<.<<.........<......<<<<<<..<<<.........>>>...<<<<
<<.............>>>>>>....<<<.<<<<.....>>>>..>>>...
.>>.>>>>.....>..>>.>>>>>>>>>>>>.>>...........<<<<<
.......>>>>>.......<<..<<<.<<<...<<<<<.<<<<<<..<<<
<<.<<<<<<<<.......>>>>>>>>>>>>>..<<<<((((.>>>><<<<
<<...........>>>>>>...<.....<<<..<<<<.....>>>>..>>
>....>.......<<<....>>>............>>>>..>>>>>>>.<
<<<<<<<<...<<.......>>...>>>>>>>>>.....)))).<<<<<.
.<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>
.....>>>>>......>>>>>.....<<<<<<<....>>>.>>>>...>>
>..>>>.>>...<<<.<<<.................>>>.>>><<<<<..
.<<<....>>>.>>>>>......<<<.<............>.>>>.....
..........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of0 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		A48 R49 G50 N51 E52 Y53 Q54 P55 S56 N57 K59 R60 K61 N62 K63 H64 G65 W66 V67 R69 A74 V78 R81 R82 K85 G86 R87 K88 H92
Binding residue
(residue number reindexed from 1)		A1 R2 G3 N4 E5 Y6 Q7 P8 S9 N10 K12 R13 K14 N15 K16 H17 G18 W19 V20 R22 A27 V31 R34 R35 K38 G39 R40 K41 H45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of0, PDBe:7of0, PDBj:7of0
PDBsum7of0
PubMed34135319
UniProtQ9BQ48|RM34_HUMAN Large ribosomal subunit protein bL34m (Gene Name=MRPL34)

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