Structure of PDB 6vbu Chain 2 Binding Site BS01

Receptor Information
>6vbu Chain 2 (length=659) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQPVFTLKLRHKISPRMVAVGRYDGTHPCLAAATQAGKVFIHNPDVSLLN
INQTVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA
SAIVLGTLGDITSPLAIIGGNCALQGFNHEGNDLFWTVTGDNVHSLALCD
FDGDGKKELLVGSEDFDIRVFKEDEIVAEMSETEIITSLCPMYGSRFGYA
LSNGTVGVYDKTARYWRIKSKNQAMSIHAFDLNSDGVCELITGWSNGKVD
ARSDRTGEVIFKDNFSSAIAGVVEGDYRMEGCQQLICCSVDGEIRGYLPI
RELSQKKQNLLLELRNYEENAGVIPANTKHHTALSVSLGAHAELCISTSN
DTIIRAVLIFAEGVFAGESHVVHPSVHHLSSSVRIPITPPKDIPVDLHLK
TFVGYRSSTQFHVFELTRQLPRFSMYALTSPDPASEPLSYVNFIIAERAQ
RVVMWLNQNFLLPEDTNIQNAPFQVCFTSLRNGGQLYIKIKLSGEITVNT
DDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQ
KLSADMADNSNLIRSLLVQAEDARLMRDMKTMKNRYKELYDLNKDLLNGY
KIRCNNHTELLGSLKAVNQAIQRAGHLRVGKPKNQVITACRDAIRSNNIN
MLFRIMRVG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6vbu Chain 2 Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6vbu Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		D251 N253 D255 V257 E259
Binding residue
(residue number reindexed from 1)		D231 N233 D235 V237 E239
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:1905515 non-motile cilium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0034451 centriolar satellite
GO:0034464 BBSome
GO:0060170 ciliary membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6vbu, PDBe:6vbu, PDBj:6vbu
PDBsum6vbu
PubMed31939736
UniProtQ32L13

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