Structure of PDB 6spd Chain 2 Binding Site BS01

Receptor Information
>6spd Chain 2 (length=53) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVQQNKKSRSARDMRRSHDALESNALSVEKSTGEVHLRHHVSPDGFYRGR
KVV
Ligand information
>6spd Chain A (length=2851) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaagugaagaagcgcauacgguggaugccuuggcagucagaggcgaug
aaagacgugguagccugcgaaaagcuucggggagucggcaaacagacuuu
gauccggagaucucugaaugggggaacccaccuaggauaaccuagguauc
uuguacugaauccauaggugcaagaggcgaaccaggggaacugaaacauc
uaaguacccugaggaaaagaaaucaaccgagauucccuuaguaguggcga
gcgaacggggauuagcccuuaagcuauuuuagcggaacgcucuggaaagu
gcggccauagugggugauagccccguacgcgaaaggaucuuugaagugaa
aucaaguaggacggagcacgagaaacuuugucugaacauggggggaccau
ccuccaaggcuaaauacuacugacugaccgauagugaaccaguaccguga
gggaaaggcgaaaagaaccccggagaggggagugaaauagaccugaaacc
guaugcguacaagcagugggagccuacuuguuaggugacugcguaccuuu
uguauaaugggucagcgacuuauauucaguggcaagcuuaaccguauagg
guaggcguagcgaaagcgagucuuaauagggcguagucgcuggguauaga
cccgaaaccgggcgaucuauccaugagcagguugaagguuagguaacacu
gacuggaggaccgaacccacucccguugaaaagguaggggaugacuugug
gaucggagugaaaggcuaaucaagcucggagauagcugguucuccucgaa
agcuauuuagguagcgccucauguaucacucugggggguagagcacuguu
ucggcuagggggucaucccgacuuaccaaaccgaugcaaacuccgaauac
ccagaagugagcaugggagacacacggcgggugcuaacguccgucgugaa
aagggaaacaacccagaccgccagcuaaggucccaaaguugugguuaagu
gguaaacgaugugggaaggcuuagacagcuaggagguuggcuuagaagca
gccacccuuuaaagaaagcguaauagcucacuagucgagucggccugcgc
ggaagauguaacggggcaaccacacaccgaagcugcgggugucacguaag
ugacgcgguagaggagcguucuguaagccugugaaggugaguugagaagc
uugcuggagguaucagaagugcgaaugcugacaugaguaacgacaauggg
ugugaaaaacacccacgccgaaagaccaaggguuccugcgcaacguuaau
cgacgcaggguuagucgguuccuaaggcgaggcugaaaagcguagucgau
gggaaacagguuaauauuccuguacuucugguuacugcgauggagggacg
gagaaggcuaggccagcuuggcguugguuguccaaguuuaaggugguagg
cugaaaucuuagguaaauccgggguuucaaggccgagagcugaugacgag
ucguagaugacgaagugguugaugccaugcuuccaagaaaagcuucuaag
cuucagguaaccaggaaccguaccccaaaccgacacagguggucggguag
agaauaccaaggcgcuugagagaacucgggugaaggaacuaggcaaaaug
gcaccguaacuucgggagaaggugcgccggcuagugaaaagcucuggcug
gucgaagauaccaggccgcugcgacuguuuauuaaaaacacagcacucug
caaacacgaaaguggacguauagggugugacgccugcccggugccggaag
guuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccggua
aacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucgg
guaaguuccgaccugcacgaauggcguaacgauggcggcgcugucuccac
ccgagacucagugaaauugaaaucgcugugaagaugcaguguauccgcgg
cuagacggaaagaccccgugaaccuuuacuguagcuuugcacuggacuuu
gagccugcuuguguaggauaggugggaggcuuugaagcguggacgccagu
ucgcguggagccauccuugaaauaccacccuggcaugcuugagguucuaa
cucugguccguaauccggaucgaggacaguguauggugggcaguuugacu
ggggcggucuccuccuaaagaguaacggaggaguacgaaggugcgcucag
accggucggaaaucggucgcagaguauaaaggcaaaagcgcgcuugacug
cgagacagacacgucgagcagguacgaaaguaggucuuagugauccggug
guucuguauggaagggccaucgcucaacggauaaaagguacuccggggau
aacaggcugauaccgcccaagaguucauaucgacggcgguguuuggcacc
ucgaugucggcucaucacauccuggggcugaagccggucccaaggguaug
gcuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugag
acaguucggucccuaucugccguggacguuugagauuugagaggggcugc
uccuaguacgagaggaccggaguggacgaaccucuggguuccgguuguca
cgccaguggcauugccggguagcuauguucggaaaagauaaccgcugaaa
gcaucuaagcgggaaacuugccucaagaugagaucucacugggaacuuga
uuccccugaagggccgucgaagacuacgacguugauaggcugggugugua
agcguugugaggcguugagcuaaccaguacuaaugcccgugaggcuugac
c
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<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<......>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...(((........<<<<..<<<...<<<.<......>.
>>>((......<<<.....))>>>...>>>....>>>>............
........<<<<<<<<.........>>>>>>>>......<<<<<..<<<<
>>>>>..)))......]].>>>>>>>.]]...............<<....
>>....]].........<<<<.....>>>>............}....>>>
>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>...<.<..
......>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<.....>>
...>>>...<<....>>..<<<<<...>>>>>...>>>>>>>>>>>>>..
<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>
>>>>.....>>>...<<<.<<.<<........>>.>>>>>....>>>>>>
>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<...
.<<<<<....>>>>>.<<<<<<<<.....<<<<<<.....<<<...<<<.
<<<<...<..<<<.......>>>...>...>>>>.>>>..>>.>.....>
>>>>..>...>>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<..<<........<<<<<..<...<<<.........
>>>...>.........<<<......>>>..>>>>>....>>..>>>>>.>
>...........)))...>>>>>>.>>>...>>>>>>><<<<<<......
>>>>>>....>>>>>><.<<<<<...<<<......<<<<<<<<....>>>
>>>>>...>>>..>>>>>..>.....>>>>>><......<<.....<<<<
<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....
>>.>>>>>>....((<<<<<<<...<<<...<<<....>>>...>>>...
>>>..<<<<<........>>>>>))<<<<<<<<<<<.<...<<<<....<
<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<....<<
<.<<<<<<<..<<.....>>.>>>>>>>...>>>....>>>...>><..<
<<<....>>>>...>>>>>>...>>>...>>>.>........>>>>...>
.....>>>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.
....>>>>..>>>>..<<<<....<<<<<<<<.<<...............
<<<<<....<<..>>.....>>>>><<<<<<..<<.....>>....>>>>
>>............<<<<<<<<<..<<<.........>>>..<<<<<<<.
....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<
<<........<<<<<<.<<....>>..>>>>>>........>>>>>>>>.
.>>>>><<<<<.........>>>>>........<...........<<<<<
.......>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>
>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<
<.(((.[[......<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<
<<<<.<<<<...........<<<<<...........<.<.<<<<....>>
>>.>.>..................>>>>>..>>>>.>>>>>>>>>>>...
<<<.<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<
.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<
<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<
<..<<<......>>>..>>>>.<<<....>>>.>>)))]......<<<<<
<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>...
....<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>.
......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<
<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>
>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<
<<<...............>>>>>>>.<<<<<...<<<...<<<<<<<<<<
.)))..>>>>>..>>>>>....>>>.>>>>>...<<<.<..<<<<<....
.......>>>>>...>>>>.>>>>.......>>>>>>>..<<<<<.....
>>>>>.....<<<<<<<<<.......>>>>>....<<<<<<<<..<<...
..<<<......>>>....>>...>>>>>.>>>..>>>>.....>>>>>>>
.
Receptor-Ligand Complex Structure
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PDB6spd Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution3.28 Å
Binding residue
(original residue number in PDB)
A2 V3 Q4 Q5 K8 S9 S11 R13 R16 R17 H19 N25 R39 H40 R49
Binding residue
(residue number reindexed from 1)
A1 V2 Q3 Q4 K7 S8 S10 R12 R15 R16 H18 N24 R38 H39 R48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0015934 large ribosomal subunit

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6spd, PDBe:6spd, PDBj:6spd
PDBsum6spd
PubMed31611393
UniProtA0A069QB25

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