Structure of PDB 5zwm Chain 2 Binding Site BS01

Receptor Information
>5zwm Chain 2 (length=211) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPSLSQLKSQVPYPQIIEWYDCDARYPGLLASIKCTKNVIPVPSHWQSKK
EYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPALDLDYKKLHDVFFKIG
ANWKPDHLLCFGDVYYENRNLFEETNWKRMVDHKRPGRISQELRAIMNLP
EGQLPPWCMKMKDIGLPTGYPDLKIAGLNWDITNLKGDVYGKIIPRNYFG
ALISFETPEFE
Ligand information
>5zwm Chain H (length=206) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugaguguaguaucuguucuuuucaguguaacaacugaaaug
accuaggcucauacauuuuuuggcacggacgggaagaggguggcgcugca
agaggaaguuuuucgauuguugauuuuccuuuugaaguguccucgagacg
ucgcgacccucggagucguucuugacuuggucgcuugauguuucuucuuc
ccguuc
.............................<<<<<<......>>>>>>.<<
<<<..>>.>>>................<<<<<<<<<<..<.<<<<<<.<<
<<<<<<<<.<<..<<..>>..>>.>>>>>>>>>>.>>>>>>.>.<<<<<<
<<<<<<.<<...<<<<<<....>>>>>>>>>>>>..>>>>>>>>.>>>>>
>>>>>.
Receptor-Ligand Complex Structure
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PDB5zwm Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.4 Å
Binding residue
(original residue number in PDB)		W149 D153 Q177
Binding residue
(residue number reindexed from 1)		W19 D23 Q47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwm, PDBe:5zwm, PDBj:5zwm
PDBsum5zwm
PubMed29794219
UniProtQ02554|CUS1_YEAST Cold sensitive U2 snRNA suppressor 1 (Gene Name=CUS1)

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