Structure of PDB 5gan Chain 2 Binding Site BS01

Receptor Information
>5gan Chain 2 (length=90) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLFFSFFKTLVDQEVVVELKNDIEIKGTLQSVDQFLNLKLDNISCTDEKK
YPHLGSVRNIFIRGSTVRYVYLNKNMVDTNLLQDATRREV
Ligand information
>5gan Chain W (length=80) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaacuucguggacauuuggucaauuugaauacagagaucagcag
uuccccugcauaaggaugaaccguuguuuu
<<<<<<<<<.>>>>>>>>>.........<<<..>>>..............
..............................
Receptor-Ligand Complex Structure
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PDB5gan Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		D12 Q13 F35 N37 R63 G64 S65 K74 N75 M76 V77 D78 T79 N80 L81 D84
Binding residue
(residue number reindexed from 1)		D12 Q13 F35 N37 R63 G64 S65 K74 N75 M76 V77 D78 T79 N80 L81 D84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 mRNA splicing, via spliceosome
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000932 P-body
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005688 U6 snRNP
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:1990726 Lsm1-7-Pat1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5gan, PDBe:5gan, PDBj:5gan
PDBsum5gan
PubMed26829225
UniProtP38203|LSM2_YEAST U6 snRNA-associated Sm-like protein LSm2 (Gene Name=LSM2)

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