Structure of PDB 4v19 Chain 2 Binding Site BS01

Receptor Information
>4v19 Chain 2 (length=178) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNMLL
TLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEKA
RPGAWRRDIFGRIIWHKFKQWPIPWYLNKKYNRKRFFAMPYVERFVRMRI
EKQARIKARKRSLERKKEKFLQEKFPHL
Ligand information
>4v19 Chain A (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacaacaaauacaaaaauacaccaaaauaaaauaaa
acauucaccuaacauuaaaguauaggagauagaaauuuuuauccugacgc
uauagagauaguaccguaagggaaagaugaaagaauaaaaguaaaaaaaa
gcaaagauuaccccuucuaccuuuugcauaaugguuuaaccagaaaaaau
cuaacaaagagaacuuuagcuagauaccccgaaaccagacgagcuaccca
ugagcaguuuaaaagaaccaacucaucuauguggcaaaauagugagaaga
cuuguagguagaggugaaaagccuaacgagccuggugauagcugguuguc
cgagaaagaauuuuaguucaaccuuaaaaauaccccaaaaacccuaaauu
ccaauguauuuuuaagagauagucuaaaaagguacagcuuuuuagaaacg
gauacaaccuugacuagagaguaaaucuuaauacuaccauaguaggccua
aaagcagccaucaauugagaaagcguuaaagcucaacaaauucaccaaca
uaaucccaaaaacuaauaacaaacuccuagcccaauaccggacuaaucua
uugaaacauagaagcaauaauguuaauaugaguaacaagaagccuuucuc
cucgcacacgcuuacaucaguaacuaauaauauacugauaauuaacaacc
aauaaaccaaaacaacacuaaaacguuuauuaauuacauuguuaacccaa
cacaggagugcaccaaggaaagauuaaaagaaguaaaaggaacucggcaa
acacaaaccccgccuguuuaccaaaaacaucaccucuagcauuacuagua
uuagaggcaaugccugcccagugacaaguuuaacggccgcgguacugacc
gugcaaagguagcauaaucacuuguucuccaaauaaggacuuguaugaau
ggccacacgaggguuuuacugucucuuacuuccaaucagugaaauuaacc
uucccgugaagaggcgggaauaaaaaaauaagacgagaagacccuaugga
gcuuuaauuaacuauuccaaaaguucuuaacauggacuagcaauuucggu
uggggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagac
aaaccagucaaaauaaucacuuauugauccaaaauuuugaucaacggaac
aaguuacccuagggauaacagcgcaauccuguucuagaguuccuaucgac
aauaggguuuacgaccucgauguuggaucaggacacccaaauggugcagc
cgcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugag
uucagaccggagcaauccaggucgguuucuaucuauuauaaauuucuccc
aguacgaaaggacaagagaaaugggaccaaccucacaaacgcgucucaga
gauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaauccagcc
cuagaacagggcaca
<<.......<<<<<.................................<..
....>...........<.....<<.....>>....>.........>>.>>
>............<<....>>...................>>........
...<<<.......>>>...<.<........>.>..<<<<<........<<
<<<.<..<<....>>...>.>>>>>..<<.<...<<<<.<.....<<<.<
<<<<..<<<......>>>...<<<..<<<<........>>>>.>>>....
>>>>>.>>>...<<<.....>>>......>.>>>>......>.>>..<<<
<<.....<<<<....>>>>...<<<<<<<<<<<.....<<........>>
.....>>>>>>>>>>>......<<<<<<<<<......>>>>>>>>>...<
<......>>....<<<<.<<<..................<....<<<...
......>>>....>.......<<<......>>>.................
.......................>>>>>>>........>>>>>...<<<<
<......>>>>>.........>>>>>.<......<<..<<<<..>>>><<
<..<<<<........<<<<<....<<....>>..>>>>>......<<<..
<<<<<<<.................>>>>>>>.......>>>.....<<..
....>>.>>>>.....>>>..<<<<....<<<<<<<.<<...........
....<<<<<<<<..<<<.........>>>...<<<<<<............
.>>>>>>...<<<<.<<<..<<<<<..>>>..>>>>><<<<<<....>>>
>>>........<...........<<<<<.......>>>>>.....>....
>>>.>..>>.>>>>>>......>>.>>>>>>>.>>>>.>>.....>....
.<<<<<........>>>>>.......<<<.<<<.<<......<<<<.<<<
<<<..<<<<..<<<.<<<<.<<<..>>>....>>>>.>>>.>>>>..<<<
<.....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<
......>>>...>>.>>>>..........<<<<..>>>>...........
.>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...
>>>>>>...>.>>.>.......<.<<<.<<<<<<..<<.<<<<<<.....
.>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>..>
....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<<<<<..
...............>>>>>>><<<<<...............>>>>>.<<
<.<.<<<<.................>>>>..>>>>.>>.........<<<
<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4v19 The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Resolution3.4 Å
Binding residue
(original residue number in PDB)		Q119 K122 R125 R166 I174 K182 K184 P187 I188 Y191 L192 N193 K194 N197 R198 K199 R200 F202 M204 R224 L228 K232
Binding residue
(residue number reindexed from 1)		Q54 K57 R60 R101 I109 K117 K119 P122 I123 Y126 L127 N128 K129 N132 R133 K134 R135 F137 M139 R159 L163 K167
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005761 mitochondrial ribosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v19, PDBe:4v19, PDBj:4v19
PDBsum4v19
PubMed25271403
UniProtF1SGC7

[Back to BioLiP]