Structure of PDB 8ud8 Chain 1i Binding Site BS01 |
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>8ud8 Chain 1a (length=1500)
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uuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaaga caugcaagucgugcgggccgcggguccguggucagcggcggacgggugag uaacgcgugggugaccuacccggaagagggggacaacccggggaaacucg ggcuaaucccccauguggacccgccccuugggguguguccaaagggcuuu gcccgcuuccggaugggcccgcgucccaucagcuaguuggugggguaaug gcccaccaaggcgacgacggguagccggucugagaggauggccggccaca ggggcacugagacacgggccccacuccuacgggaggcagcaguuaggaau cuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaagaa gcccuucgggguguaaacuccugaacccgggacgaaacccccgacgaggg gacugacgguaccgggguaauagcgccggccaacuccgugccagcagccg cgguaauacggagggcgcgagcguuacccggauucacugggcguaaaggg cguguaggcggccuggggcgucccaugugaaagaccacggcucaaccgug ggggagcgugggauacgcucaggcuagacggugggagagggugguggaau ucccggaguagcggugaaaugcgcagauaccgggaggaacgccgauggcg aaggcagccaccugguccacccgugacgcugaggcgcgaaagcgugggga gcaaaccggauuagauacccggguaguccacgcccuaaacgaugcgcgcu aggucucugggucuccugggggccgaagcuaacgcguuaagcgcgccgcc uggggaguacggccgcaaggcugaaacucaaaggaauugacgggggcccg cacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaaccuua ccaggccuugacaugcuagggaacccgggugaaagccuggggugccccgc gaggggagcccuagcacaggugcugcauggccgucgucagcucgugccgu gagguguuggguuaagucccgcaacgagcgcaacccccgccguuaguugc cagcgguucggccgggcacucuaacgggacugcccgcgaaagcgggagga aggaggggacgacgucuggucagcauggcccuuacggccugggcgacaca cgugcuacaaugcccacuacaaagcgaugccacccggcaacggggagcua aucgcaaaaaggugggcccaguucggauuggggucugcaacccgacccca ugaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaauac guucccgggccuuguacacaccgcccgucacgccaugggagcgggcucua cccgaagucgccgggagccuacgggcaggcgccgaggguagggcccguga cuggggcgaagucguaacaagguagcuguaccggaaggugcggcuggauc |
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<< <.<<<..<<<..<<.<<<<<<<<..>>>>>>>>.>>>>>......<<... ....<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>> >>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<... >>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<...... .>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>. <<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>..... ...<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<...... <<<<....>>>>.....>>>>....<<<<<........<<<<.....>>> >..........>>>>>......<<<<<(((...<<<<<.....<<.)))> >.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....< <<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>> >....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....< <<<<<<.<..<<<......>>>.....>.>>>>>>>...........<<. ...>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<... <<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<. .<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>> .<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<< .<<.<<<<<<..<<<<<<<<<<......<<........>>.......... <<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.<..<<... ...>>.>..>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.. ..>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<..<< <..<<<.....>>>>>>...>>>>>>>.....<<<<<....>>>>>.... ....>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>> >>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>.. ..>>>.....>>>>>>>......<....<<<<<<<........>>>>>>> ....>.....>>>>>>....<<<<<<<..........>>>>>>>...... >>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<< <<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>.. >>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>..... |
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PDB | 8ud8 An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance |
Resolution | 2.6 Å |
Binding residue (original residue number in PDB) | Q3 Y5 T7 R9 K11 E12 V14 R16 F18 R20 Y36 Q38 G39 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 K127 R128 |
Binding residue (residue number reindexed from 1) | Q2 Y4 T6 R8 K10 E11 V13 R15 F17 R19 Y35 Q37 G38 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 K126 R127 |
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Enzyme Commision number |
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