Structure of PDB 5v8i Chain 1F Binding Site BS01

Receptor Information
>5v8i Chain 1F (length=202) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRG
EVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKV
RKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVL
LVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNR
IG
Ligand information
>5v8i Chain 1A (length=2862) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga
cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc
uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc
gcgcggggggaaccuggggaacugaaacaucucaguacccagaggagagg
aaagagaaaucgacucccugaguagcggcgagcgaaaggggaccagccua
aaccguccggcuuguccgggcggggucguggggcccucggaccgaauccc
cagccuagccgaagcuguugggaagcagcgccagagagggugaaagcccc
guaggcgaaagguggggggauaggugaggguacccgaguaccccgugguu
cguggagccaugggggaaucugggcggaccaccgccuaaggcuaaguacu
ccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaagaacc
ccgggaggggagugaaauagagccugaaaccgugggcuuacaagcaguca
cggccccgagggguuguggcgugccuauugaagcaugagccggcgacuca
cggucgugggcgagcuuaagccguugaggcggaggcguagggaaaccgag
uccgaacagggcgucuaguccgcggccguggacccgaaaccgggcgagcu
agcccuggccagggugaagcuggggugagacccaguggaggcccgaaccg
gugggggaugcaaaccccucggaugagcuggggcuaggagugaaaagcua
accgagcccggagauagcugguucuccccgaaaugacuuuagggucagcc
ucaggcgcugacuggggccuguagagcacugauagggcuagggggcccac
cagccuaccaaacccugucaaacuccgaagggucccagguggagccuggg
agugagggcgcgagcgauaacguccgcguccgagcgcgggaacaaccgag
accgccagcuaaggcccccaagucugggcuaagugguaaaggauguggcg
ccgcgaagacagccaggagguuggcuuagaagcagccauccuuuaaagag
ugcguaauagcucacuggucgaguggcgccgcgccgaaaaugaucggggc
ucaagcccagcgccgaagcugcgggucugggggaugaccccaggcgguag
gggagcguucccgaugccgaugaaggccgacccgcgagggcggcuggagg
uaagggaagugcgaaugccggcaugaguaacgauaaagagggugagaauc
ccucucgccguaagcccaaggguuccuacgcaauggucgucagcguaggg
uuaggcgggaccuaaggugaagccgaaaggcguagccgaagggcagccgg
uuaauauuccggcccuucccgcaggugcgauggggggacgcucuaggcua
gggggaccggagccauggacgagcccggccagaagcgcagggugggaggu
aggcaaauccgccucccaaaagcucugcgugguggggaagcccgggugac
aaccccccgaagccagggagccaagaaaagccucuaagcacaaccugcgg
gaacccguaccgcaaaccgacacaggugggcgggugcaagagcacucagg
cgcgcgggagaacccucgccaaggaacucugcaaguuggccccguaacuu
cgggagaaggggugcucccuggggugaugagcuccggggagccgcaguga
acaggcucuggcgacuguuuaccaaaaacacagcucucugcgaacucgua
agaggagguauagggagcgacgcuugcccggugccggaaggucaagggga
ggggugcaagccccgaaccgaagccccggugaacggcggccguaacuaua
acgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcacg
aaaagcguaacgaccggagcgcugucucggcgagggacccggugaaauug
aacuggccgugaagaugcggccuacccguggcaggacgaaaagaccccgu
ggagcuuuacugcagccugguguuggcucuuggucgcgccugcguaggau
aggugggagccugugaacccccgccuccgggugggggggaggcgccggug
aaauaccacccuggcgcggcugggggccuaacccucggauggggggacag
cgcuuggcgggcaguuugacuggggcggucgccuccuaaaagguaacgga
ggcgcccaaagguccccucaggcgggacggaaauccgccggagagcgcaa
ggguagaagggggccugacugcgaggccugcaagccgagcaggggcgaaa
gccgggccuagugaaccgguggucccguguggaagggccaucgaucaacg
gauaaaaguuaccccggggauaacaggcugaucucccccgagcguccaca
gcggcggggagguuuggcaccucgaugucggcucgucgcauccuggggcu
gaagaaggucccaaggguugggcuguucgcccauuaaagcggcacgcgag
cuggguucagaacgucgugagacaguucggucucuauccgccacgggcgc
aggaggcuugaggggggcucuuccuaguacgagaggaccggaagggacgc
accucugguuucccagcugucccuccaggggcauaagcuggguagccaug
ugcggaagggauaaccgcugaaagcaucuaagcgggaagcccgccccaag
augaggccucccacggcagccgguaaggacccgggaagacgacccggugg
augggccggggguguaagcgccgcgaggcguugagccgaccggucccaau
cguccgaggucu
<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<<
<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>>
>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<.
.>>>>>.>>...<<<<<<.....<......>......>>>>>.>......
...<<....>>...<<<<<.....<<.....>>....>>>>>...<<<..
..<<<<<<<<.....>>>>>>>>......<<<<<<<<<..<<<...<<<<
<.<<<<.<<<...<<<<<......>>>>>((......<<<.....))>>>
...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<<<<<<<<.
......>>>>>>>>>......<<<<<..((((>>>>>..>>>......>>
.>>>>>>.>>...............<<....>>....>>.........<<
<<....>>>>..................>>>>>>>>>>>.......<<<<
<<<<<<<..>>>>>>>>>>>...<............>.<<<<<<....<<
<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<....>>..<
<<<.....>>>>.....>>>>>>>>>>>>>..<<.<...<<<<<<.....
<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<
..<<<<........>>>>.>>>....>>>>>>>>>...<<<.....>>>.
.....>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<
<<<<<<.....<<<<<<<<<...<<<...<<<<<<<<...<<<<<<....
..>>>>.>>...>>>>>>>>..>>.>...>>>>>>>>>.....>>>>>>>
.>>..<<<<<<<.<<......>>.>>>>>>>.....<<<......>>>..
.<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<
<<<........<<<<<.<<....<<.........>>....>>........
.<<......>>...>>>>>....>>>>>>>>>.>>..........)))..
....>>>>>>.>>>...>>>>>>><<<<<<<<.....>>>>>>>>....>
>>>>>..<<<<<...<<<......<<<<<.<<<....>>>>>>>>...>>
>..>>>>>........>>>>>><......<<.....<<<<<<.......>
>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>.
...((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<
........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<<.<<<..
<<<<<.<<<<.<<..[[[[...>>>>>><<<...<<<<<<<<<<<<<<<<
.<<.....>>>>>>>>>....>>>>>>>>>..>>>....<<<..>>>...
...>>>>>...>>>..>>>>>.........>>>>...>>...>>>>>>>>
>>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>
>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.....<.
.>......>>>>><<<<<<<<<<<<.....>>>>>>>>>>>>........
....<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<...
.>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<...
<<<<<....>>>>>...>>...>>>>>>>>..>>>>><<<<<<.......
>>>>>>........<...........<<<<<<.....>>>>>>.....>.
...>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.
....<<<<<........>>>>>..<<<<<<<<.<<<.........<<<<.
<<<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<<<<<<..........
.<<<<<..<<<......<<<<<<<......>>>>>>>...>>>.......
.....>>>>>..>>>>>>>>>>>>>>>>...<<<<<....>>>>>....>
>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>
>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(
((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....
>>>.>>))).......<<<<<<<.<<..))))..>>>>>>>>>.......
......>>>>..>>>>>>.......<<<<.<.<<<<<<...<<.......
>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<
......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>...>
>>.>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>...
.<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<
<<...<<<<...<<<<<<<<<<<]]]]>>>>>>...>>>>>...>>>>.>
>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>...
....>>>>>>>..<<<<.>>>>....<<<<<<<<<.......>>>>>...
.<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>..
.>>>>....>>>
Receptor-Ligand Complex Structure
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PDB5v8i Structural robustness of the ribosome inferred from X-ray crystal structures of the 30S ribosomal subunit and the 70S ribosome lacking ribosomal protein uS17
Resolution3.25 Å
Binding residue
(original residue number in PDB)
N29 H31 W34 E35 R38 Q40 L41 K43 R44 R45 R46 T48 A49 S50 T51 T53 R54 G55 V57 A58 Y59 S60 R62 K63 Q67 K68 H69 R72 R74 H75 G76 I82 F83 V84 G85 V89 F90 P92 P94 Y99 T100 P102 K103 K104 R106 K108 G134 K135 T136 R165 R168 N169 P171 G180 Y184 R205
Binding residue
(residue number reindexed from 1)
N24 H26 W29 E30 R33 Q35 L36 K38 R39 R40 R41 T43 A44 S45 T46 T48 R49 G50 V52 A53 Y54 S55 R57 K58 Q62 K63 H64 R67 R69 H70 G71 I77 F78 V79 G80 V84 F85 P87 P89 Y94 T95 P97 K98 K99 R101 K103 G129 K130 T131 R160 R163 N164 P166 G175 Y179 R200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5v8i, PDBe:5v8i, PDBj:5v8i
PDBsum5v8i
PubMed
UniProtQ72I05|RL4_THET2 Large ribosomal subunit protein uL4 (Gene Name=rplD)

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